Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 17/20 | 0.56 |
| ▸ | PGR | P06401 | 14/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5355175 | 1.00 | NR3C1 (0.56) | NR3C1NR3C2PGRARMAPT | |
| SCHEMBL5370067 | 0.88 | NR3C1 (0.53) | NR3C1NR3C2PGRAR | |
| SCHEMBL5370062 | 0.88 | NR3C1 (0.53) | NR3C1NR3C2PGRAR | |
| SCHEMBL4476447 | 0.81 | NR3C1 (0.63) | NR3C1NR3C2PGRARMAPT | |
| SCHEMBL5349055 | 0.81 | NR3C1 (0.54) | NR3C1NR3C2PGRARMAPT | |
| SCHEMBL5360216 | 0.81 | NR3C1 (0.54) | NR3C1NR3C2PGRARMAPT | |
| SCHEMBL5349049 | 0.81 | NR3C1 (0.54) | NR3C1NR3C2PGRARMAPT | |
| SCHEMBL6510765 | 0.81 | NR3C1 (0.54) | NR3C1NR3C2PGRARMAPT | |
| SCHEMBL5349050 | 0.81 | NR3C1 (0.54) | NR3C1NR3C2PGRARMAPT | |
| SCHEMBL5360211 | 0.81 | NR3C1 (0.54) | NR3C1NR3C2PGRARMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256300-B2 | Stereoselective synthesis of certain trifluoromethyl-substituted alcohols | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2007-08-14 | — | — | US | disclosed |
| US-7256300-B2 | Stereoselective synthesis of certain trifluoromethyl-substituted alcohols | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2007-08-14 | — | — | US | disclosed |
| US-20050234250-A1 | Stereoselective synthesis of certain trifluoromethyl-substituted alcohols | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234250-A1 | Stereoselective synthesis of certain trifluoromethyl-substituted alcohols | NR3C1, NR3C2, MC2R | NR3C1 1/4885NR3C2 2/4885PGR 414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.