SCHEMBL53553

SCHEMBL53553

CC1(C(=O)O)CCCCN1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.39
ARG1 P05089 1/20 0.33
ARG2 P78540 1/20 0.33
CYP2C19 P33261 1/20 0.31
PARP1 P09874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25372775 1.00 FFAR3 (0.39) FFAR3ARG1ARG2CYP2C19PARP1
SCHEMBL14488376 1.00 FFAR3 (0.39) FFAR3ARG1ARG2CYP2C19PARP1
Hydrochloric Acid SCHEMBL16584573 0.98 FFAR3 (0.37) FFAR3ARG1ARG2CYP2C19
Hydrochloric Acid SCHEMBL5968897 0.98 FFAR3 (0.37) FFAR3ARG1ARG2CYP2C19
Hydrochloric Acid SCHEMBL927105 0.98 FFAR3 (0.37) FFAR3ARG1ARG2CYP2C19
SCHEMBL697443 0.93
SCHEMBL573927 0.93
SCHEMBL3325667 0.93
Hydrochloric Acid SCHEMBL17393208 0.91 FFAR3 (0.39) FFAR3ARG1ARG2PARP1
Bromide SCHEMBL14659502 0.91 FFAR3 (0.39) FFAR3ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9573934-B2 Methods and compositions for the synthesis of multimerizing agents ARIAD PHARMACEUTICALS, INC. (US) 2017-02-21 US claimed
US-20150148543-A1 Methods and Compositions for the Synthesis of Multimerizing Agents TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-05-28 US claimed
US-9024028-B2 Methods and compositions for the synthesis of multimerizing agents ARIAD PHARMACEUTICALS, INC. (US) 2015-05-05 US claimed
US-20140171649-A1 Methods and Compositions for the Synthesis of Multimerizing Agents ARIAD PHARMACEUTICALS, INC. (US) 2014-06-19 US claimed
WO-2012103279-A2 METHODS AND COMPOSITIONS FOR THE SYNTHESIS OF MULTIMERIZING AGENTS ARIAD PHARMACEUTICALS, INCORPORATED (US) 2012-08-02 WO claimed
EP-1773877-B1 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL MYERS SQUIBB CO (US) 2010-03-17 EP claimed
CN-101400699-A Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions BRISTOL MYERS SQUIBB CO (US) 2009-04-01 CN claimed
EP-1976873-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS Brystol-Myers Squibb Company (US) 2008-10-08 EP claimed
US-20070238669-A1 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY 2007-10-11 US claimed
CN-101010339-A Human glucagon-like-peptide-1 modulators and their use in treatment of diabetes and related conditions BRISTOL MYERS SQUIBB CO (US) 2007-08-01 CN claimed
WO-2007082264-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY (US) 2007-07-19 WO claimed
EP-1773877-A1 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS Bristol-Myers Squibb Company (US) 2007-04-18 EP claimed
US-20060287242-A1 Human glucagon-like-peptide-1 modulators and their use in treatment of diabetes and related conditions BRISTOL-MYERS SQUIBB COMPANY 2006-12-21 US claimed
WO-2006014287-A1 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY (US) 2006-02-09 WO claimed
EP-0378318-A1 Process for synthesis of FK-506 and tricarbonyl intermediates MERCK & CO. INC. (US) 1990-07-18 EP claimed
EP-4151622-B1 AROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN DRUG SICHUAN ACAD OF MEDICAL SCIENCES SICHUAN PROVINCIAL PEOPLES HOSPITAL (CN) 2026-05-06 EP disclosed
US-20240168029-A1 APPLICATION OF COMPOSITION IN PREPARATION OF DRUG FOR DIAGNOSING INFANTILE HEMANGIOMA AND/OR MONITORING PROGRESS AND PROGNOSIS THEREOF, AND KIT AND DRUG JIANG CHENGHONG (CN) 2024-05-23 US disclosed
US-5164525-A SYNTHETIC PROCESS FOR FK-506 TYPE MACROLIDE INTERMEDIATES MERCK & CO., INC. (US) 1992-11-17 US disclosed
EP-0405994-A2 Synthetic process for FK-506 type macrolide intermediates MERCK & CO. INC. (US) 1991-01-02 EP disclosed
EP-0378318-A1 Process for synthesis of FK-506 and tricarbonyl intermediates MERCK & CO. INC. (US) 1990-07-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070238669-A1 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS GLP1R, GIPR, IAPP FFAR3 95/4885ARG1 829/4885ARG2 798/4885
US-20140171649-A1 Methods and Compositions for the Synthesis of Multimerizing Agents PIP5K1C, PIP4K2C, IPMK FFAR3 2153/4885ARG1 2677/4885ARG2 3452/4885
US-20060287242-A1 Human glucagon-like-peptide-1 modulators and their use in treatment of diabetes and related conditions GLP1R, GIPR, IAPP FFAR3 101/4885ARG1 694/4885ARG2 760/4885
US-20150148543-A1 Methods and Compositions for the Synthesis of Multimerizing Agents PARG, POLI, MCM6 FFAR3 4869/4885ARG1 3961/4885ARG2 4275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.