Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5288710 | 0.82 | SLC1A3 (0.48) | CYP2C9CYP2C19HPGDHTTALDH1A1 | |
| SCHEMBL11014440 | 0.79 | CYP2C9 (0.42) | CYP2C9CYP2C19HPGDHTTALDH1A1 | |
| SCHEMBL3927861 | 0.78 | RAB9A (0.47) | CYP2C9CYP2C19ALDH1A1CYP1A2PPARG | |
| SCHEMBL447136 | 0.78 | CYP2C9 (0.48) | CYP2C9CYP2C19HPGDHTTALDH1A1 | |
| SCHEMBL27533979 | 0.77 | ALDH1A1 (0.42) | CYP2C9CYP2C19HPGDHTTALDH1A1 | |
| SCHEMBL5319467 | 0.77 | CYP2C9 (0.51) | CYP2C9CYP2C19HPGDHTTALDH1A1 | |
| SCHEMBL10268819 | 0.74 | ACE (0.51) | CYP2C9CYP2C19HPGDHTTALDH1A1 | |
| SCHEMBL10827609 | 0.74 | CYP2C9 (0.47) | CYP2C9CYP2C19HPGDHTTALDH1A1 | |
| SCHEMBL5321314 | 0.74 | SLC1A3 (0.46) | CYP2C9CYP2C19HPGDHTTALDH1A1 | |
| SCHEMBL599642 | 0.73 | CYP2C9 (0.43) | CYP2C9CYP2C19HPGDHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002469-A2 | THERAPEUTIC COMPOSITIONS AND METHODS USING TRANSFORMING GROWTH FACTOR-BETA MIMICS | BHATNAGAR RAJENDRA S (US) | 2007-01-04 | — | — | WO | disclosed |