Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5354914 | 1.00 | CA2 (0.37) | CA2CA1CA9ALDH1A1 | |
| SCHEMBL7799360 | 0.84 | SMN1; SMN2 (0.37) | CA2CA1CA9ALDH1A1 | |
| SCHEMBL5695104 | 0.84 | CA2 (0.40) | CA2CA1CA9ALDH1A1 | |
| SCHEMBL5367628 | 0.84 | CA2 (0.40) | CA2CA1CA9ALDH1A1 | |
| SCHEMBL5358550 | 0.84 | CA2 (0.40) | CA2CA1CA9ALDH1A1 | |
| SCHEMBL10305250 | 0.84 | CA2 (0.40) | CA2CA1CA9ALDH1A1 | |
| SCHEMBL21449039 | 0.82 | CA2 (0.34) | CA2CA1CA9 | |
| SCHEMBL8322168 | 0.82 | CA2 (0.34) | CA2CA1CA9 | |
| SCHEMBL17170416 | 0.82 | CA2 (0.34) | CA2CA1CA9 | |
| SCHEMBL2621335 | 0.82 | CA2 (0.34) | CA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189706-B2 | C2,5′-disubstituted and N6,C2,5′-trisubstituted adenosine derivatives and pharmaceutical compositions containing them | UNIVERSITEIT LEIDEN (NL) | 2007-03-13 | — | — | US | disclosed |
| US-20040127452-A1 | C2,5'-disubstituted and N6,C2,5'-trisubstituted adenosine derivatives and pharmaceutical compositions containing them | UNIVERSITEIT LEIDEN (NL) | 2004-07-01 | — | — | US | disclosed |
| US-20010011075-A1 | 5'-SUBSTITUTED-RIBOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | TOWNSEND LEROY B (US) | 2001-08-02 | — | — | US | disclosed |
| US-5874413-A | CYTOMEGALO VIRUS | UNIVERSITY OF MICHIGAN (US) | 1999-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127452-A1 | C2,5'-disubstituted and N6,C2,5'-trisubstituted adenosine derivatives and pharmaceutical compositions containing them | ADORA2A, ADORA3, ADORA1 | CA2 1681/4885CA1 4117/4885CA9 3524/4885 |
| US-20010011075-A1 | 5'-SUBSTITUTED-RIBOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | ZC3HAV1, ZC3HAV1L, IFNAR1 | CA2 3725/4885CA1 4050/4885CA9 4002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.