Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.60 |
| ▸ | FLT3 | P36888 | 2/20 | 0.60 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | XDH | P47989 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 4/20 | 0.48 |
| ▸ | SRC | P12931 | 4/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1144995 | 0.86 | HPGD (0.62) | GLAGAAHRH4FLT3IDO1 | |
| SCHEMBL17324813 | 0.86 | FLT3 (0.61) | GLAGAAHRH4FLT3IDO1 | |
| SCHEMBL6518654 | 0.85 | GAA (0.51) | GLAGAAHRH4FLT3IDO1 | |
| SCHEMBL3276252 | 0.85 | KDM4E (0.57) | GLAGAAHRH4FLT3IDO1 | |
| SCHEMBL1277561 | 0.84 | XDH (0.59) | GLAGAAHRH4FLT3IDO1 | |
| SCHEMBL3283667 | 0.83 | NSD2 (0.61) | GLAGAAHRH4XDHDRD2 | |
| SCHEMBL10509208 | 0.83 | XDH (0.50) | GLAGAAHRH4FLT3XDH | |
| SCHEMBL10507997 | 0.82 | HRH4 (0.52) | GLAGAAHRH4FLT3IDO1 | |
| SCHEMBL24019646 | 0.82 | IDO1 (0.62) | GLAGAAHRH4FLT3IDO1 | |
| SCHEMBL17321408 | 0.82 | FLT3 (0.57) | GLAGAAHRH4FLT3IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307098-B2 | Indole derivatives and drugs containing the same | MEIJI DAIRIES CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |
| US-20050261357-A1 | Indole derivatives and drugs containing the same | MEIJI DAIRIES CORPORATION (JP) | 2005-11-24 | — | — | US | disclosed |
| EP-1533299-A1 | INDOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | Meiji Dairies Corporation (JP) | 2005-05-25 | — | — | EP | disclosed |
| US-4835175-A | Indole derivatives pharmaceutical preparations based thereon, and β-receptor stimulation therewith | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261357-A1 | Indole derivatives and drugs containing the same | IDO1, TPH1, IDO2 | GLA 3351/4885GAA 4746/4885HRH4 355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.