Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | PDE3B | Q13370 | 7/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.55 |
| ▸ | PDE2A | O00408 | 5/20 | 0.55 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | FABP1 | P07148 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978731 | 0.84 | PTPN7 (0.66) | MCL1PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL30539402 | 0.82 | PTPN7 (0.67) | PDE3BPDE3APDE2AP2RY12PPARA | |
| SCHEMBL20886118 | 0.82 | PTPN7 (0.67) | PDE3BPDE3APDE2AP2RY12PPARA | |
| SCHEMBL23412215 | 0.81 | ALDH1A1 (0.58) | MCL1PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL9950393 | 0.80 | PPARG (0.60) | MCL1PPARAPPARGALDH1A1CYSLTR2 | |
| SCHEMBL4315187 | 0.80 | NPC1 (0.55) | MCL1PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL6483474 | 0.80 | PTPN7 (0.60) | PDE3BPDE3APDE2AP2RY12PPARA | |
| Bromide SCHEMBL592843 | 0.80 | ALOX5 (0.56) | MCL1PDE3BPDE3AP2RY12PPARA | |
| SCHEMBL26125762 | 0.79 | ALDH1A1 (0.50) | MCL1PPARAPPARGALDH1A1ALOX5 | |
| SCHEMBL5398136 | 0.79 | PPARG (0.50) | MCL1PPARAPPARGALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507509-B2 | Saturated and insaturated bi- or tricyclic aryloxyacetamine derivatives and their use as fungicides | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-13 | — | — | US | disclosed |
| EP-2185518-B1 | Aryloxyacetamide derivatives and their use as fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2012-02-08 | — | — | EP | disclosed |
| US-20100298356-A1 | SATURATED AND INSATURATED BI- OR TRICYCLIC ARYLOXYACETAMINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-11-25 | — | — | US | disclosed |
| EP-2185518-A2 | SATURATED AND INSATURATED BI- OR TRICYCLIC ARYLOXYACETAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | Syngenta Participations AG (CH) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009030467-A2 | SATURATED AND INSATURATED BI- OR TRICYCLIC ARYLOXYACETAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG, (CH) | 2009-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298356-A1 | SATURATED AND INSATURATED BI- OR TRICYCLIC ARYLOXYACETAMINE DERIVATIVES AND THEIR USE AS FUNGICIDES | CYP1A2, CYP1B1, CYP1A1 | MCL1 1502/4885PDE3B 2928/4885PDE3A 2101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.