Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 10/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351270 | 0.80 | PTH1R (0.77) | PTH1R | |
| SCHEMBL5355993 | 0.80 | PTH1R (0.53) | PTH1RALDH1A1MEN1KMT2A | |
| SCHEMBL5319870 | 0.78 | PTH1R (0.60) | PTH1RMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5352610 | 0.76 | PTH1R (0.54) | PTH1R | |
| SCHEMBL5328340 | 0.76 | PTH1R (0.50) | PTH1RMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5366388 | 0.74 | PTH1R (0.54) | PTH1RMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5347210 | 0.71 | PTH1R (0.65) | PTH1R | |
| SCHEMBL5326104 | 0.71 | PTH1R (0.45) | PTH1R | |
| SCHEMBL5362907 | 0.69 | PTH1R (0.55) | PTH1R | |
| SCHEMBL5351237 | 0.68 | PTH1R (0.54) | PTH1RALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135350-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | disclosed |