Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.89 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL233710 | 0.94 | EPHX2 (1.00) | EPHX2HSD11B1MAPTTSHRHTT | |
| Piperazine SCHEMBL5324447 | 0.93 | EPHX2 (0.97) | EPHX2HSD11B1MAPTTSHRHTT | |
| Hydrochloric Acid SCHEMBL10319192 | 0.93 | EPHX2 (0.97) | EPHX2HSD11B1MAPTTSHRHTT | |
| SCHEMBL22668886 | 0.86 | EPHX2 (0.73) | EPHX2HSD11B1MAPTTSHRHTT | |
| SCHEMBL14803888 | 0.86 | EPHX2 (0.65) | EPHX2HSD11B1 | |
| SCHEMBL22669112 | 0.85 | EPHX2 (0.71) | EPHX2HSD11B1MAPTTSHRHTT | |
| SCHEMBL31419319 | 0.79 | EPHX2 (0.64) | EPHX2HSD11B1MAPTTSHRHTT | |
| SCHEMBL30582914 | 0.79 | EPHX2 (0.64) | EPHX2HSD11B1MAPTTSHRHTT | |
| SCHEMBL30582903 | 0.79 | EPHX2 (0.64) | EPHX2HSD11B1MAPTTSHRHTT | |
| SCHEMBL30582905 | 0.78 | EPHX2 (0.62) | EPHX2HSD11B1MAPTTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007122411-A1 | DIAZEPAN-1-YL-SULFONYL DERIVATIVES FOR THE TREATMENT OF METABOLIC SYNDROME | ASTRAZENECA AB (SE) | 2007-11-01 | — | — | WO | disclosed |