SCHEMBL31419319

SCHEMBL31419319

FC(F)(F)c1cccnc1N1CCCN1

nearest known ligand 0.64

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.64
HSD11B1 P28845 9/20 0.46
MAPT P10636 1/20 0.45
TSHR P16473 1/20 0.45
HTT P42858 1/20 0.45
HSD17B10 Q99714 1/20 0.45
GAA P10253 1/20 0.43
RBP4 P02753 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5356587 0.79 EPHX2 (0.89) EPHX2HSD11B1MAPTTSHRHTT
SCHEMBL233710 0.78 EPHX2 (1.00) EPHX2HSD11B1MAPTTSHRHTT
SCHEMBL30093003 0.78 EPHX2 (0.43) EPHX2HSD11B1MAPT
Piperazine SCHEMBL5324447 0.77 EPHX2 (0.97) EPHX2HSD11B1MAPTTSHRHTT
Hydrochloric Acid SCHEMBL10319192 0.77 EPHX2 (0.97) EPHX2HSD11B1MAPTTSHRHTT
SCHEMBL28179378 0.76 HSD11B1 (0.39) EPHX2HSD11B1
SCHEMBL22668886 0.76 EPHX2 (0.73) EPHX2HSD11B1MAPTTSHRHTT
SCHEMBL22669112 0.74 EPHX2 (0.71) EPHX2HSD11B1MAPTTSHRHTT
SCHEMBL16339825 0.71 GRIN1 (0.42) EPHX2
SCHEMBL1366662 0.70 EPHX2 (0.69) EPHX2HSD11B1MAPTTSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4745134-A1 PROTEIN ARGINASE METHYLTRANSFERASE-5 INHIBITOR AND MEDICAL USE THEREOF Jiangsu Yahong Meditech Co., Ltd. (CN) 2026-05-20 EP disclosed
WO-2025016323-A1 PROTEIN ARGINASE METHYLTRANSFERASE-5 INHIBITOR AND MEDICAL USE THEREOF 江苏亚虹医药科技股份有限公司 2025-01-23 WO disclosed