SCHEMBL5356746

SCHEMBL5356746

CC(C)(N=NC(C)(C(=N)Nc1ccc(O)cc1)C(Cl)Cl)C(=N)Nc1ccc(O)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.34
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 1/20 0.34
CA12 O43570 1/20 0.34
BRD4 O60885 1/20 0.34
NR1I2 O75469 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
MB P02144 1/20 0.34
CYP1A1 P04798 1/20 0.34
CA3 P07451 1/20 0.34
CYP3A4 P08684 1/20 0.34
RARG P13631 1/20 0.34
TSHR P16473 1/20 0.34
ALOX5AP P20292 1/20 0.34
CA4 P22748 1/20 0.34
CA7 P43166 1/20 0.34
KMT2A Q03164 1/20 0.34
NR1I3 Q14994 1/20 0.34
CA9 Q16790 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5349175 0.89 SMN1; SMN2 (0.36) MAPTALDH1A1MEN1TSHRKMT2A
SCHEMBL5359274 0.87 MAPT (0.41) MAPTALDH1A1MEN1CYP3A4TSHR
SCHEMBL3861642 0.86 MAPT (0.44) MAPTALDH1A1MEN1CA12BRD4
SCHEMBL3861649 0.86 MAPT (0.44) MAPTALDH1A1MEN1CA12BRD4
Hydrochloric Acid SCHEMBL3893006 0.85 MAPT (0.42) MAPTALDH1A1MEN1CA12BRD4
Hydrochloric Acid SCHEMBL235512 0.85 MAPT (0.42) MAPTALDH1A1MEN1CA12BRD4
SCHEMBL3863419 0.75 NPC1 (0.44) MAPTALDH1A1MEN1TSHRKMT2A
SCHEMBL3863416 0.75 NPC1 (0.44) MAPTALDH1A1MEN1TSHRKMT2A
SCHEMBL22462283 0.73 NPC1 (0.42) MAPTALDH1A1MEN1TSHRKMT2A
Hydrochloric Acid SCHEMBL237195 0.73 NPC1 (0.42) MAPTALDH1A1MEN1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7216969-B2 Image recording method CANON FINETECH INC. (JP) 2007-05-15 US disclosed
US-20050212885-A1 Image recording method CANON FINETECH INC (JP) 2005-09-29 US disclosed