SCHEMBL5359274

SCHEMBL5359274

CC(C)(N=NC(C)(C(=N)Nc1ccccc1)C(Cl)Cl)C(=N)Nc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.41
HSP90AA1 P07900 2/20 0.41
GPR55 Q9Y2T6 1/20 0.41
ALDH1A1 P00352 7/20 0.36
GAA P10253 5/20 0.36
ATM Q13315 2/20 0.36
LMNA P02545 2/20 0.36
ABCC9 O60706 1/20 0.36
KCNJ11 Q14654 1/20 0.36
HPGD P15428 6/20 0.33
SMN1; SMN2 Q16637 4/20 0.33
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
HTT P42858 2/20 0.33
PDK1 Q15118 2/20 0.33
PDK2 Q15119 2/20 0.33
PDK3 Q15120 2/20 0.33
PDK4 Q16654 2/20 0.33
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5356746 0.87 MAPT (0.34) MAPTALDH1A1GAALMNAHPGD
SCHEMBL5349175 0.87 SMN1; SMN2 (0.36) MAPTALDH1A1GAALMNASMN1; SMN2
Hypochlorous Acid SCHEMBL8937952 0.86 MAPT (0.41) MAPTHSP90AA1GPR55ALDH1A1GAA
SCHEMBL2864723 0.86 TAS2R38 (0.42) MAPTHSP90AA1GPR55ALDH1A1GAA
SCHEMBL2864721 0.86 TAS2R38 (0.42) MAPTHSP90AA1GPR55ALDH1A1GAA
Hydrochloric Acid SCHEMBL305248 0.84 TAS2R38 (0.41) MAPTHSP90AA1GPR55ALDH1A1GAA
Hydrochloric Acid SCHEMBL238225 0.84 TAS2R38 (0.41) MAPTHSP90AA1GPR55ALDH1A1GAA
Hydrochloric Acid SCHEMBL8596813 0.84 TAS2R38 (0.41) MAPTHSP90AA1GPR55ALDH1A1GAA
SCHEMBL5353443 0.76 RIPK1 (0.38) MAPTALDH1A1GAALMNAHPGD
SCHEMBL3863419 0.73 NPC1 (0.44) MAPTALDH1A1GAALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7216969-B2 Image recording method CANON FINETECH INC. (JP) 2007-05-15 US disclosed
US-20050212885-A1 Image recording method CANON FINETECH INC (JP) 2005-09-29 US disclosed