SCHEMBL535685

SCHEMBL535685

COc1cc(N)cc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.50
MAPT P10636 4/20 0.47
IDO1 P14902 1/20 0.47
EP300 Q09472 2/20 0.46
TLR8 Q9NR97 1/20 0.46
KAT8 Q9H7Z6 1/20 0.46
ALDH1A1 P00352 3/20 0.43
ADRA2B P18089 1/20 0.43
PTGS1 P23219 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
LMNA P02545 1/20 0.43
HPGD P15428 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
GAA P10253 2/20 0.42
KDM4E B2RXH2 1/20 0.42
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
ALOX15 P16050 1/20 0.41
CA12 O43570 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL22445135 0.98 EP300 (0.48) NQO1MAPTIDO1EP300TLR8
SCHEMBL11312377 0.91 ALDH1A1 (0.60) NQO1MAPTIDO1EP300TLR8
Naphthylamine SCHEMBL7136311 0.91 ALDH1A1 (0.57) NQO1MAPTIDO1EP300TLR8
SCHEMBL5748845 0.85 NQO1 (0.57) NQO1MAPTIDO1EP300TLR8
Alanine SCHEMBL28618174 0.84 ALOX15 (0.44) NQO1EP300ALDH1A1PTGS1HPGD
SCHEMBL2479530 0.80 ALDH1A1 (0.43) MAPTALDH1A1TDP1LMNASMN1; SMN2
SCHEMBL28784490 0.79 ALDH1A1 (0.39) NQO1TLR8ALDH1A1TDP1HPGD
SCHEMBL8197756 0.79 NQO1 (0.54) NQO1MAPTALDH1A1LMNAHPGD
Leucine SCHEMBL11418818 0.79 SLC7A5 (0.45) MAPTALDH1A1LMNAHPGDKDM4E
SCHEMBL229214 0.78 PLAU (0.53) NQO1MAPTIDO1EP300TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 629 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117305407-A Ureaplasma typing detection kit 郑州安图生物工程股份有限公司 2023-12-29 CN claimed
EP-3198281-B1 ELLAGIC ACID FORMULATIONS FOR USE IN COAGULATION ASSAYS ABBOTT POINT OF CARE INC (US) 2023-01-25 EP claimed
EP-3198280-B1 SENSORS FOR ASSAYING COAGULATION IN FLUID SAMPLES ABBOTT POINT OF CARE INC (US) 2021-05-26 EP claimed
US-10746749-B2 Ellagic acid formulations for use in coagulation assays ABBOTT POINT OF CARE INC. (US) 2020-08-18 US claimed
US-20180196072-A1 ELLAGIC ACID FORMULATIONS FOR USE IN COAGULATION ASSAYS ABBOTT POINT OF CARE INC. (US) 2018-07-12 US claimed
US-9921232-B2 Ellagic acid formulations for use in coagulation assays ABBOTT POINT OF CARE INC. (US) 2018-03-20 US claimed
US-9903877-B2 Sensors for assaying coagulation in fluid samples ABBOTT POINT OF CARE INC. (US) 2018-02-27 US claimed
EP-3198281-A1 ELLAGIC ACID FORMULATIONS FOR USE IN COAGULATION ASSAYS Abbott Point Of Care, Inc. (US) 2017-08-02 EP claimed
EP-3198280-A1 SENSORS FOR ASSAYING COAGULATION IN FLUID SAMPLES Abbott Point Of Care, Inc. (US) 2017-08-02 EP claimed
US-20160091512-A1 ELLAGIC ACID FORMULATIONS FOR USE IN COAGULATION ASSAYS ABBOTT POINT OF CARE INC. 2016-03-31 US claimed
US-4440678-A ARGININES PENTAPHARM, A.G. (CH) 1984-04-03 US claimed
US-4428874-A QUANTITATIVE ANALYSIS OF PROTEOLYTIC ENZYMES PENTAPHARM A.G. (CH) 1984-01-31 US claimed
EP-0019589-B1 TRIPEPTIDE DERIVATIVES AND THEIR USE IN A PROCESS FOR DETERMINING ENZYMES Pentapharm A.G. (CH) 1983-11-09 EP claimed
EP-0034122-B1 TRIPEPTIDE DERIVATIVES AND THEIR USE IN THE DETERMINATION OF ENZYMES Pentapharm A.G. (CH) 1983-09-21 EP claimed
EP-0018002-B1 PROCESS FOR THE DETERMINATION OF PROTEASES AND ANTIPROTEASES Jozefonvicz, Marcel (FR) 1983-02-09 EP claimed
EP-0016800-A4 Determination of proteolytic enzymes in body fluids and fluorogenic substrates. AMERICAN HOSPITAL SUPPLY CORP (US) 1981-01-08 EP claimed
EP-0018002-A1 Process for the determination of proteases and antiproteases Jozefonvicz, Marcel (FR) 1980-10-29 EP claimed
US-4229528-A Fluorescence method for enzyme analysis which couples aromatic amines with aromatic aldehydes SMITH ROBERT E 1980-10-21 US claimed
EP-0016800-A1 Determination of proteolytic enzymes in body fluids and fluorogenic substrates. AMERICAN HOSPITAL SUPPLY CORP (US) 1980-10-15 EP claimed
WO-1980000351-A1 ANALYTICAL FLUOROGENIC SUBSTRATES FOR PROTEOLYTIC ENZYMES AMERICAN HOSPITAL SUPPLY CORP (US) 1980-03-06 WO claimed