Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4492210 | 0.98 | KDM4E (0.56) | HTR2CKDM4ELMNAADRA2AADRA1A | |
| SCHEMBL3393178 | 0.94 | HTR2C (0.61) | HTR2CKDM4ELMNAADRA2AADRA1A | |
| Hydrochloric Acid SCHEMBL4487208 | 0.93 | KDM4E (0.62) | HTR2CKDM4ELMNAADRA2AADRA1A | |
| SCHEMBL13268865 | 0.87 | ADRA2A (0.48) | HTR2CADRA2AADRA1AMAPTBLM | |
| SCHEMBL2302053 | 0.87 | ADRA2A (0.48) | HTR2CADRA2AADRA1AMAPTBLM | |
| SCHEMBL22510580 | 0.87 | ADRA2A (0.48) | HTR2CADRA2AADRA1AMAPTBLM | |
| SCHEMBL3393335 | 0.86 | HTR2C (0.60) | HTR2CKDM4ELMNAADRA2AADRA1A | |
| SCHEMBL13098013 | 0.84 | HTR2C (0.66) | HTR2CKDM4ELMNAADRA2AADRA1A | |
| Hydrochloric Acid SCHEMBL1177554 | 0.84 | HTR2C (0.58) | HTR2CKDM4ELMNAADRA2AADRA1A | |
| SCHEMBL3819574 | 0.84 | HTR2C (0.62) | HTR2CKDM4ELMNAADRA2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7287646-B2 | Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy | PHOTOCURE ASA (NO) | 2007-10-30 | — | — | US | claimed |
| US-20050107471-A1 | NEW ESTERS OF 5-AMINOLEVULINIC ACID AND THEIR USE AS PHOTOSENSITIZING COMPOUNDS IN PHOTOCHEMOTHERAPY | GIERSKCKY KARL E (NO) | 2005-05-19 | — | — | US | claimed |