Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4487208 | 0.98 | KDM4E (0.62) | HTR2CKDM4ELMNAADRA2AADRA1A | |
| SCHEMBL5356898 | 0.94 | HTR2C (0.56) | HTR2CKDM4ELMNAADRA2AADRA1A | |
| Hydrochloric Acid SCHEMBL4492210 | 0.93 | KDM4E (0.56) | HTR2CKDM4ELMNAADRA2AADRA1A | |
| SCHEMBL13098013 | 0.89 | HTR2C (0.66) | HTR2CKDM4ELMNAADRA2AADRA1A | |
| SCHEMBL813361 | 0.85 | ADRA2A (0.54) | HTR2CKDM4ELMNAADRA2AADRA1A | |
| SCHEMBL12611805 | 0.84 | HTR2C (0.71) | HTR2CKDM4ELMNAADRA2AADRA1A | |
| SCHEMBL987127 | 0.82 | HTR2C (0.73) | HTR2CKDM4ELMNAADRA2AADRA1A | |
| SCHEMBL2568519 | 0.81 | TSHR (0.44) | HTR2CKDM4ELMNAADRA2AADRA1A | |
| SCHEMBL3819574 | 0.81 | HTR2C (0.62) | HTR2CKDM4ELMNAADRA2AADRA1A | |
| SCHEMBL2883395 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7287646-B2 | Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy | PHOTOCURE ASA (NO) | 2007-10-30 | — | — | US | claimed |
| US-20050107471-A1 | NEW ESTERS OF 5-AMINOLEVULINIC ACID AND THEIR USE AS PHOTOSENSITIZING COMPOUNDS IN PHOTOCHEMOTHERAPY | GIERSKCKY KARL E (NO) | 2005-05-19 | — | — | US | claimed |
| US-8546447-B2 | Treatment of acne using derivatives of 5-aminolevulinic acid | PHOTOCURE ASA (NO) | 2013-10-01 | — | — | US | disclosed |
| US-20130066256-A1 | Treatment of Acne Using Derivatives of 5-Aminolevulinic Acid | PHOTOCURE ASA (NO) | 2013-03-14 | — | — | US | disclosed |
| EP-1814534-B1 | DERIVATIVES OF 5-AMINOLEVULINIC ACID FOR THE TREATMENT OF ACNE | PHOTOCURE ASA (NO) | 2010-06-02 | — | — | EP | disclosed |
| US-20080188558-A1 | Treatment of Acne Using Derivatives of 5-Aminolevulinic Acid | PHOTOCURE ASA (NO) | 2008-08-07 | — | — | US | disclosed |
| EP-1814534-A1 | TREATMENT OF ACNE USING DERIVATIVES OF 5-AMINOLEVULINIC ACID | Photocure ASA (NO) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006051269-A1 | TREATMENT OF ACNE USING DERIVATIVES OF 5-AMINOLEVULINIC ACID | PHOTOCURE ASA (NO) | 2006-05-18 | — | — | WO | disclosed |