Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | KDM4A | O75164 | 2/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.45 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CCR1 | P32246 | 2/20 | 0.44 |
| ▸ | CCR5 | P51681 | 2/20 | 0.44 |
| ▸ | CCR8 | P51685 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14444173 | 0.84 | KDM4E (0.45) | MEN1KMT2AKDM4EALOX15HSD17B10 | |
| SCHEMBL17057294 | 0.77 | SMN1; SMN2 (0.42) | MEN1KMT2AKDM4EALOX15TSHR | |
| SCHEMBL18989524 | 0.73 | CYP2C9 (0.39) | MEN1KMT2AKDM4EKDM3AMAPK1 | |
| SCHEMBL16397208 | 0.73 | SMN1; SMN2 (0.35) | MEN1KMT2ATSHRSMN1; SMN2LMNA | |
| SCHEMBL2773101 | 0.73 | HPGDS (0.56) | MEN1KMT2AHPGDSKDM4EMAPK1 | |
| SCHEMBL10271336 | 0.73 | KDM4E (0.55) | MEN1KMT2AKDM4EMAPK1ALOX15 | |
| SCHEMBL5360711 | 0.72 | MEN1 (0.65) | MEN1KMT2AKDM4EKDM4AKDM6B | |
| Dipyridyl SCHEMBL28774978 | 0.71 | KDM4E (0.61) | MEN1KMT2AHPGDSKDM4EKDM4A | |
| SCHEMBL30037083 | 0.71 | KDM4E (0.57) | MEN1KMT2AKDM4EKDM4AKDM6B | |
| SCHEMBL1669165 | 0.71 | KDM4E (0.57) | MEN1KMT2AKDM4EKDM4AKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238697-B2 | Pyridylpyrimidines for use as pesticides | BAYER CROPSCIENCE AG (DE) | 2007-07-03 | — | — | US | disclosed |
| US-20040077641-A1 | Pyridyl pyrimidines for use as pesticides | BAYER CROPSCIENCE AG (DE) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077641-A1 | Pyridyl pyrimidines for use as pesticides | PNPO, P2RX6, P2RX1 | MEN1 3315/4885KMT2A 3530/4885HPGDS 3001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.