SCHEMBL5357080

SCHEMBL5357080

Cc1cc(C(C)(C)C)cc(C(C)(C)C)c1OCC(CO)(CO)CO

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RXRA P19793 11/20 0.36
PPARG P37231 9/20 0.36
RARG P13631 4/20 0.36
RXRB P28702 4/20 0.36
RXRG P48443 4/20 0.36
RARA P10276 3/20 0.36
RARB P10826 3/20 0.36
HTR1D P28221 2/20 0.33
HTR1B P28222 1/20 0.33
ELANE P08246 1/20 0.33
CD69 Q07108 1/20 0.33
POLB P06746 1/20 0.32
HSP90AA1 P07900 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5347930 0.92 RXRA (0.38) RXRAPPARGRARGRXRBRXRG
SCHEMBL27305016 0.83 CYP2C9 (0.31) HSP90AA1ALDH1A1
SCHEMBL27280928 0.82 RXRA (0.35) RXRAPPARGRARGRXRBRXRG
SCHEMBL2232697 0.81 SMN1; SMN2 (0.44) POLBALDH1A1
SCHEMBL27893433 0.78 CYP3A4 (0.39) RXRAPPARGRARGRXRBRXRG
SCHEMBL28979480 0.77 ALDH1A1 (0.50) ALDH1A1
SCHEMBL3106078 0.77 CYP2D6 (0.43) POLBALDH1A1
SCHEMBL992037 0.77 TRPV1 (0.41) RXRARXRBRXRGALDH1A1
SCHEMBL28610704 0.77 CYP2D6 (0.43) POLBALDH1A1
SCHEMBL27523155 0.75 HSPA5 (0.44) RARBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117321151-A Composition comprising flaky transition metal particles 巴斯夫欧洲公司 2023-12-29 CN disclosed
EP-3807339-A1 TRANSESTERIFICATION METHOD FOR SIMULTANEOUSLY PRODUCING AT LEAST TWO DIFFERENT POLYCARBONATES IN A PRODUCTION FACILITY Covestro Intellectual Property GmbH & Co. KG (DE) 2021-04-21 EP disclosed
CN-112368313-A Polyurethane foam or polyether polyol stabilized with benzofuranone-phosphite derivatives 巴斯夫欧洲公司 2021-02-12 CN disclosed
CN-112166148-A Flame retardant rotomolding polyolefin 巴斯夫欧洲公司 2021-01-01 CN disclosed
CN-111936317-A Method for producing strongly adherent (embossed) films on flexible substrates 巴斯夫欧洲公司 2020-11-13 CN disclosed
CN-111328293-A Polycarbonate compositions 巴斯夫欧洲公司 2020-06-23 CN disclosed
WO-2019238419-A1 TRANSESTERIFICATION METHOD FOR SIMULTANEOUSLY PRODUCING AT LEAST TWO DIFFERENT POLYCARBONATES IN A PRODUCTION FACILITY COVESTRO DEUTSCHLAND AG (DE) 2019-12-19 WO disclosed
CN-101775155-A polymer stabilizer SUMITOMO CHEMICAL CO 2010-07-14 CN disclosed
US-7255814-B2 Flame retardant and stabilizer combined for thermoplastics polymers CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2007-08-14 US disclosed
WO-2005121234-A2 FLAME RETARDED POLYMER COMPOSITION WITH IMPROVED THERMAL STABILITY SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2005-12-22 WO disclosed
US-20040227130-A1 Flame retardant and stabilizer combined for thermoplastics polymers CLARIANT GMBH 2004-11-18 US disclosed