SCHEMBL5357253

SCHEMBL5357253

Fc1cc(F)c(F)c(Bc2cc(F)cc(F)c2F)c1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.41
CES1 P23141 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6063555 0.87 CES2 (0.37) CES2CES1
SCHEMBL6063044 0.87 CES2 (0.33) CES2CES1
SCHEMBL6062535 0.85 CES2 (0.35) CES2CES1
SCHEMBL6064009 0.82 CES2 (0.33) CES2CES1
SCHEMBL6063949 0.82 RAPGEF4 (0.32) CES2CES1
SCHEMBL6063379 0.82 CES2 (0.31) CES2CES1
SCHEMBL26167913 0.79 CES2 (0.43) CES2CES1
SCHEMBL6063462 0.79 CES2 (0.31) CES2CES1
SCHEMBL6063431 0.78 TUBB1 (0.36)
SCHEMBL6062963 0.77 CES2 (0.31) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7217676-B2 Hydrophobization and silica for supported catalyst EXXON MOBIL CHEMICAL PATENTS INC. (US) 2007-05-15 US disclosed
US-20060264320-A1 Hydrophobization and silica for supported catalyst RODRIGUEZ GEORGE 2006-11-23 US disclosed
US-20050159299-A1 Hydrophobization and silica for supported catalyst EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-21 US disclosed