SCHEMBL5357263

SCHEMBL5357263

Bc1c(F)cc(F)c(F)c1C

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.31
CA2 P00918 3/20 0.31
CA4 P22748 2/20 0.31
CA12 O43570 1/20 0.31
CA7 P43166 1/20 0.31
CA13 Q8N1Q1 1/20 0.31
RAPGEF4 Q8WZA2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18721406 0.82
SCHEMBL169896 0.80 CA1 (0.38) CA1CA2CA4CA12CA7
SCHEMBL5352193 0.79 HDAC1 (0.31)
SCHEMBL14327159 0.75 CES2 (0.38) CA1CA2CA4CA12CA7
SCHEMBL27397315 0.75 CA1 (0.35) CA1CA2CA4CA12CA7
Methyl Alcohol SCHEMBL9652269 0.75 CA1 (0.40) CA1CA2CA4CA12CA7
SCHEMBL5350687 0.74 CA1 (0.38) CA1CA2CA4CA12CA7
Methoxymethane SCHEMBL27534547 0.72 CA1 (0.33) CA1CA2CA4CA12CA7
Trimethylammonium SCHEMBL28044493 0.72 CA1 (0.30) CA1CA2CA4CA12CA7
SCHEMBL21921701 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7217676-B2 Hydrophobization and silica for supported catalyst EXXON MOBIL CHEMICAL PATENTS INC. (US) 2007-05-15 US disclosed
EP-1704171-A2 HYDROPHOBIZATION AND SILICA FOR SUPPORTED CATALYST ExxonMobil Chemical Patents Inc. (US) 2006-09-27 EP disclosed
WO-2005075526-A2 HYDROPHOBIZATION AND SILICA FOR SUPPORTED CATALYST EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-08-18 WO disclosed
US-20050159299-A1 Hydrophobization and silica for supported catalyst EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-21 US disclosed