Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | MAPK13 | O15264 | 6/20 | 0.60 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.60 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23896686 | 0.93 | MAPK13 (0.67) | FABP4MAPTALOX15MAPK13MAPK12 | |
| SCHEMBL10652552 | 0.90 | MAPK13 (0.55) | FABP4MAPTALOX15MAPK13MAPK12 | |
| SCHEMBL11341624 | 0.89 | MAPK13 (0.68) | FABP4MAPTALOX15MAPK13MAPK12 | |
| SCHEMBL8442758 | 0.88 | MAPK13 (0.62) | FABP4MAPTALOX15MAPK13MAPK12 | |
| SCHEMBL14985410 | 0.86 | CXCR2 (0.57) | FABP4MAPTALOX15MAPK13MAPK12 | |
| SCHEMBL28475949 | 0.86 | MAPK13 (0.53) | FABP4MAPTALOX15MAPK13MAPK12 | |
| SCHEMBL19657886 | 0.83 | KMT2A (0.49) | FABP4MAPTALOX15MAPK13MAPK12 | |
| SCHEMBL8174226 | 0.82 | KMT2A (0.62) | MAPTKMT2AALDH1A1AKR1C3MEN1 | |
| Fenamic Acid SCHEMBL29622832 | 0.82 | FABP4 (0.92) | FABP4MAPTALOX15KMT2AALDH1A1 | |
| Fenamic Acid SCHEMBL25828 | 0.82 | FABP4 (0.92) | FABP4MAPTALOX15KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638666-B | Tire rubber composition and pneumatic tire | 住友橡胶工业株式会社 | 2023-01-10 | — | — | CN | disclosed |
| CN-109336813-B | Photocatalytic oxidation synthesis method of acridone compounds | 浙江工业大学上虞研究院有限公司 | 2021-08-10 | — | — | CN | disclosed |
| CN-112654672-A | Tread rubber composition and pneumatic tire | 住友橡胶工业株式会社 | 2021-04-13 | — | — | CN | disclosed |
| CN-112638666-A | Tire rubber composition and pneumatic tire | 住友橡胶工业株式会社 | 2021-04-09 | — | — | CN | disclosed |
| CN-109071685-B | Terminal-modified conjugated diene polymer, rubber composition, and rubber article | 株式会社普利司通 | 2020-12-01 | — | — | CN | disclosed |
| CN-104045600-B | A kind of preparation method of N-(2-hydroxy-5-methyl oxygen carbonyl phenyl) acridones compound | 中科院广州化学有限公司 | 2016-10-05 | — | — | CN | disclosed |
| CN-104045600-A | Preparation method of N-(2-hydroxy-5-methoxycarbonyl phenyl) acridone compound | CAS GUANGZHOU CHEMISTRY CO LTD | 2014-09-17 | — | — | CN | disclosed |
| US-20100171417-A1 | CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE | FUJIFILM CORPORATION (JP) | 2010-07-08 | — | — | US | disclosed |
| US-20100171417-A1 | CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE | FUJIFILM CORPORATION (JP) | 2010-07-08 | — | — | US | disclosed |
| EP-1778204-A4 | COMPOSITIONS AND METHODS RELATING TO NOVEL COMPOUNDS AND TRAGET THEREOF | UNIV MICHIGAN (US) | 2007-12-26 | — | — | EP | disclosed |
| US-20070218289-A1 | Photofunctional Laminated Article | DAIKIN INDUSTRIES, LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| US-20070197718-A1 | Photofunctional optical material comprising fluorine-containing acrylate polymer | DAIKIN INDUSTRIES LTD. | 2007-08-23 | — | — | US | disclosed |
| US-7238685-B2 | Benzo-fused heterocycles as endothelin antagonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2007-07-03 | — | — | US | disclosed |
| EP-1778204-A2 | COMPOSITIONS AND METHODS RELATING TO NOVEL COMPOUNDS AND TRAGET THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006014526-A2 | COMPOSITIONS AND METHODS RELATING TO NOVEL COMPOUNDS AND TARGETS THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2006-02-09 | — | — | WO | disclosed |
| US-20050124605-A1 | Novel benzo-fused heterocycles as endothelin antagonisits | ACTELION PHARMACEUTICALS LTD. | 2005-06-09 | — | — | US | disclosed |
| WO-2003013545-A1 | NOVEL BENZO-FUSED HETEROCYCLES AS ENDOTHELIN ANTAGONISITS | ACTELION PHARMACEUTICALS LTD (CH) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124605-A1 | Novel benzo-fused heterocycles as endothelin antagonisits | EDNRA, EDNRB, ECE1 | FABP4 3640/4885MAPT 3793/4885ALOX15 1049/4885 |
| US-20100171417-A1 | CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE | L1CAM, SLC67A1, SLC26A3 | FABP4 3193/4885MAPT 3069/4885ALOX15 3666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.