Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14559201 | 1.00 | EPHX1 (0.50) | EPHX1CYP19A1ALDH1A1HPGDTSHR | |
| SCHEMBL21623926 | 0.85 | EPHX1 (0.55) | EPHX1CYP19A1ALDH1A1HPGDTSHR | |
| SCHEMBL20328573 | 0.84 | EPHX1 (0.56) | EPHX1CYP19A1ALDH1A1HPGDTSHR | |
| SCHEMBL20719903 | 0.84 | EPHX1 (0.56) | EPHX1CYP19A1ALDH1A1HPGDTSHR | |
| SCHEMBL10139341 | 0.84 | EPHX1 (0.56) | EPHX1CYP19A1ALDH1A1HPGDTSHR | |
| SCHEMBL14822843 | 0.84 | EPHX1 (0.56) | EPHX1CYP19A1ALDH1A1HPGDTSHR | |
| SCHEMBL19670085 | 0.84 | EPHX1 (0.56) | EPHX1CYP19A1ALDH1A1HPGDTSHR | |
| SCHEMBL13253745 | 0.84 | EPHX1 (0.56) | EPHX1CYP19A1ALDH1A1HPGDTSHR | |
| SCHEMBL10139342 | 0.84 | EPHX1 (0.56) | EPHX1CYP19A1ALDH1A1HPGDTSHR | |
| SCHEMBL15135100 | 0.83 | EPHX1 (0.50) | EPHX1CYP19A1ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186854-B2 | Process for making bicalutamide and intermediates thereof | SYNTHON IP INC. (US) | 2007-03-06 | — | — | US | disclosed |
| US-6818766-B2 | USING P-FLUOROBENZENESULFINIC ACID | SYNTHON BV (NL) | 2004-11-16 | — | — | US | disclosed |
| US-20040068135-A1 | Process for making bicalutamide and intermediates thereof | SYNTHON IP INC. | 2004-04-08 | — | — | US | disclosed |
| US-20030073742-A1 | Process for making bicalutamide and intermediates thereof | SYNTHON B.V. (NL) | 2003-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073742-A1 | Process for making bicalutamide and intermediates thereof | BLVRB, BRDT, OTUB1 | EPHX1 2750/4885CYP19A1 40/4885ALDH1A1 1010/4885 |
| US-20040068135-A1 | Process for making bicalutamide and intermediates thereof | BLVRB, BRDT, OTUB1 | EPHX1 2750/4885CYP19A1 40/4885ALDH1A1 1010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.