OTUB1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL19220487	0.67	4/20
SCHEMBL19220488	0.66	4/20
SCHEMBL21498209	0.64	4/20
SCHEMBL7808410	0.62	4/20
SCHEMBL7808446	0.61	4/20
SCHEMBL7808123	0.57	4/20
SCHEMBL7808221	0.57	4/20
SCHEMBL7815859	0.62	3/20
SCHEMBL31276578	0.62	3/20
SCHEMBL19198299	0.51	3/20
SCHEMBL2401601	0.33	3/20
SCHEMBL19220486	0.74	2/20
SCHEMBL7808226	0.73	2/20
SCHEMBL29629183	0.73	2/20
SCHEMBL29629184	0.73	2/20
SCHEMBL7968066	0.62	2/20
SCHEMBL19225117	0.62	2/20
SCHEMBL7812967	0.61	2/20
SCHEMBL7808315	0.58	2/20
SCHEMBL7811858	0.57	2/20

Clinical trials — most relevant to OTUB1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Relapsed and/or Refractory Non-Hodgkin Lymphoma Study	PHASE2	WITHDRAWN
Phase II Study of Vandetanib in Individuals With Kidney Cancer	PHASE2	COMPLETED
Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma	PHASE2	WITHDRAWN
Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma	PHASE2	SUSPENDED
Studying TAK-243 in Patients With Advanced Cancer	PHASE1	RECRUITING
Impact of Nrf2 Activation on Macrovascular, Microvascular & Leg Function & Walking Capacity in Peripheral Artery Disease	EARLY_PHASE1	RECRUITING
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN
Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1	nan	RECRUITING
Muscle Wasting in Hemodialysis Patient	nan	COMPLETED
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure	nan	COMPLETED
Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas	nan	RECRUITING
Transcriptional and Epigenetic Program of PCOS Women	nan	ACTIVE_NOT_RECRUITING
The Role of RING Ubiquitin Ligases in Biologic and Oncologic Processes in Tissues of Mesenchymal Origin	nan	UNKNOWN
Genetic Variation in TRAF3IP2 (rs13190932)	nan	RECRUITING
Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors	nan	NOT_YET_RECRUITING
Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome	nan	RECRUITING
Inhibition of SENP1 for the Suppression of OS Growth and Metastasis	nan	UNKNOWN
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease	nan	UNKNOWN
Value of MicroRNA30a in Philadelphia Positive Leukemic Patients	nan	UNKNOWN
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma	nan	COMPLETED
Biomarker Panel in Ovarian Torsion	nan	UNKNOWN
RNA Cloning and Visualization in Human Atherosclerosis	nan	COMPLETED
Early Detection of Breast Cancer in Women With Suspicious Mammograms	nan	ACTIVE_NOT_RECRUITING
Safety and Tolerability of a Nutritional Formula Designed to Aid in Maintenance of Muscle During Periods of Caloric Restriction in Adults	nan	NOT_YET_RECRUITING
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders	nan	COMPLETED
Genetics and Environment iNtersection In the ALS-FTD Spectrum: an Italian Twins Cohort studY With a Multi-Omics Approach	nan	RECRUITING
Identification of a New Gene Involved in Hereditary Lipodystrophy	nan	COMPLETED
Pancreatic Intraepithelial Neoplasia (PanIN) and the Association With Recurrence of Pancreatic Adenocarcinoma	nan	COMPLETED
Establishment of a Prospective Clinical-biological Database	nan	RECRUITING
Acute Pancreatitis Targets (APT) Study	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a OTUB1 binder may also engage these)

Protein	Name	Similarity
Q7TQI3	—	1.000	Q7TQI3 →
B2RYG6	—	1.000	B2RYG6 →
Q96DC9	—	0.990	Q96DC9 →
Q9VL00	—	0.990	Q9VL00 →
Q9CQX0	—	0.986	Q9CQX0 →
Q9XVR6	—	0.973	Q9XVR6 →
A8XDJ2	—	0.971	A8XDJ2 →
Q29FC9	—	0.970	Q29FC9 →
Q9LPT6	—	0.968	Q9LPT6 →
Q9LYC7	—	0.967	Q9LYC7 →
Q9VRJ9	—	0.965	Q9VRJ9 →
Q5ZJM3	—	0.964	Q5ZJM3 →
USP7	Ubiquitin carboxyl-terminal hydrolase 7	0.963	landscape →
Q4VSI4	—	0.963	Q4VSI4 →
Q7L8S5	—	0.963	Q7L8S5 →
Q6U7I1	—	0.963	Q6U7I1 →
Q7Q068	—	0.962	Q7Q068 →
Q9FFF2	—	0.962	Q9FFF2 →
Q567B1	—	0.961	Q567B1 →
Q17D30	—	0.961	Q17D30 →
Q6NX27	—	0.961	Q6NX27 →
Q803R5	—	0.961	Q803R5 →
Q0IH43	—	0.960	Q0IH43 →
P31669	—	0.960	P31669 →
Q6NTW6	—	0.960	Q6NTW6 →
SMS	Spermine synthase	0.960	landscape →
Q6DDS9	—	0.960	Q6DDS9 →
Q6IE21	—	0.960	Q6IE21 →
Q9C5W6	—	0.960	Q9C5W6 →
P97355	—	0.960	P97355 →