Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoxaline SCHEMBL30320908 | 0.96 | ALDH1A1 (0.58) | ALDH1A1MAPTNCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL5315 | 0.96 | ALDH1A1 (0.58) | ALDH1A1MAPTNCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL6928518 | 0.96 | ALDH1A1 (0.58) | ALDH1A1MAPTNCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL29355228 | 0.96 | ALDH1A1 (0.58) | ALDH1A1MAPTNCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL9171633 | 0.93 | ALDH1A1 (0.55) | ALDH1A1MAPTNCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL9171618 | 0.93 | ALDH1A1 (0.55) | ALDH1A1MAPTNCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL16053848 | 0.93 | ALDH1A1 (0.55) | ALDH1A1MAPTNCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL7329021 | 0.93 | ALDH1A1 (0.55) | ALDH1A1MAPTNCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL2431603 | 0.93 | ALDH1A1 (0.55) | ALDH1A1MAPTNCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL2359961 | 0.93 | ALDH1A1 (0.55) | ALDH1A1MAPTNCF1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1354740-A | Pharmaceutical compounds | NICOX SA (FR) | 2002-06-19 | — | — | CN | claimed |
| CN-216704355-U | Enamel reaction kettle for hydrolysis of oxolinic acid | 大连宝盛精细化工科技有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-216704355-U | Enamel reaction kettle for hydrolysis of oxolinic acid | 大连宝盛精细化工科技有限公司 | 2022-06-10 | — | — | CN | disclosed |
| US-7202245-B2 | Substituted 4-amino[1,2,4]triazolo[4,3-a] quinoxalines | PFIZER INC. (US) | 2007-04-10 | — | — | US | disclosed |
| EP-1613629-A1 | SUBSTITUTED 4-AMINO 1,2,4 TRIAZOLO 4,3-A QUINOXALINES | Pfizer Products Inc. (US) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004085439-A1 | SUBSTITUTED 4-AMINO[1,2,4]TRIAZOLO[4,3-A]QUINOXALINES | PFIZER PRODUCTS INC. (US) | 2004-10-07 | — | — | WO | disclosed |
| US-20040192698-A1 | Substituted 4-amino[1,2,4]triazolo[4,3-a] quinoxalines | PFIZER INC. | 2004-09-30 | — | — | US | disclosed |
| CN-1354740-A | Pharmaceutical compounds | NICOX SA (FR) | 2002-06-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192698-A1 | Substituted 4-amino[1,2,4]triazolo[4,3-a] quinoxalines | CYP4B1, CYP3A4, CYP1B1 | ALDH1A1 121/4885MAPT 4029/4885NCF1 3856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.