Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL8674948 | 0.94 | CA1 (0.56) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL6562090 | 0.94 | CA1 (0.56) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL16098384 | 0.94 | CA1 (0.56) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL10821897 | 0.94 | CA1 (0.56) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL4958654 | 0.94 | CA1 (0.56) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL5491026 | 0.94 | CA1 (0.56) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL9247439 | 0.94 | CA1 (0.56) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL7608551 | 0.94 | CA1 (0.56) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL1701669 | 0.94 | CA1 (0.56) | CA4CA1FAHD1CA2CA9 | |
| Bicarbonate SCHEMBL4338785 | 0.94 | CA1 (0.56) | CA4CA1FAHD1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119240711-A | Improved pretreatment method for silicon-implanted body in laboratory | 青岛海洋科技中心 | 2025-01-03 | — | — | CN | claimed |
| CN-118892468-A | Roxithromycin capsule and preparation method thereof | 南京恒远科技开发有限公司 | 2024-11-05 | — | — | CN | claimed |
| CN-221288240-U | Heavy calcium carbonate deironing device | 河南美得装饰材料有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-111419820-B | Desloratadine citrate disodium capsule and preparation method and application thereof | 合肥医工医药股份有限公司 | 2022-03-25 | — | — | CN | claimed |
| CN-111419820-A | Desloratadine citrate disodium capsule and preparation method and application thereof | 合肥医工医药股份有限公司 | 2020-07-17 | — | — | CN | claimed |
| CN-101198558-B | Natural marble like crystallized glass and process for production thereof | NIPPON ELECTRIC GLASS CO | 2013-05-08 | — | — | CN | claimed |
| US-7111847-B2 | Self-dispensing bullet trap buffer block | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2006-09-26 | — | — | US | claimed |
| EP-1092690-B1 | Method of producing a cement with reduced content of chromium | POVAZSKA CEMENTAREN AS (SK) | 2005-07-13 | — | — | EP | claimed |
| US-20050006849-A1 | Self-dispensing bullet trap buffer block | US GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2005-01-13 | — | — | US | claimed |
| EP-1412284-A2 | COMPOSITION FOR TREATING CELLS AND METHODS FOR QUALITATIVELY AND QUANTITATIVELY CUSTOMIZING THE FORMULATION THEREOF FOR A HEURISTICALLY DERIVED LIVING CELL NUTRIENT-COMPOSITION-ON-DEMAND | Runkis, Walter H. (US) | 2004-04-28 | — | — | EP | claimed |
| US-20030073580-A1 | Composition for treating cells and method for qualitatively and quantitatively customizing the formulation thereof | RUNKIS WALTER H (US) | 2003-04-17 | — | — | US | claimed |
| WO-2002100772-A2 | COMPOSITION AND METHOD FOR TREATING CELLS AND PLANTS | RUNKIS WALTER H (US) | 2002-12-19 | — | — | WO | claimed |
| EP-1092690-A1 | Method of producing a cement with reduced content of chromium | Povazská cementáren, a.s. (SK) | 2001-04-18 | — | — | EP | claimed |
| CN-122035916-A | Whitening method for preparing precipitated calcium carbonate from high-content iron ore | 晓光新材料科技(湘西)有限公司 | 2026-05-15 | — | — | CN | disclosed |
| US-20260003096-A1 | DETERMINATION OF MINERALOGY AND LITHOLOGY FROM ELEMENTAL DATA | HALLIBURTON ENERGY SERVICES, INC. (US) | 2026-01-01 | — | — | US | disclosed |
| CN-119240711-A | Improved pretreatment method for silicon-implanted body in laboratory | 青岛海洋科技中心 | 2025-01-03 | — | — | CN | disclosed |
| EP-1412284-A2 | COMPOSITION FOR TREATING CELLS AND METHODS FOR QUALITATIVELY AND QUANTITATIVELY CUSTOMIZING THE FORMULATION THEREOF FOR A HEURISTICALLY DERIVED LIVING CELL NUTRIENT-COMPOSITION-ON-DEMAND | Runkis, Walter H. (US) | 2004-04-28 | — | — | EP | disclosed |
| US-20030073580-A1 | Composition for treating cells and method for qualitatively and quantitatively customizing the formulation thereof | RUNKIS WALTER H (US) | 2003-04-17 | — | — | US | disclosed |
| WO-2002100772-A2 | COMPOSITION AND METHOD FOR TREATING CELLS AND PLANTS | RUNKIS WALTER H (US) | 2002-12-19 | — | — | WO | disclosed |
| EP-1092690-A1 | Method of producing a cement with reduced content of chromium | Povazská cementáren, a.s. (SK) | 2001-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260003096-A1 | DETERMINATION OF MINERALOGY AND LITHOLOGY FROM ELEMENTAL DATA | DEGS1, CACNG7, LBR | CA4 1518/4885CA1 126/4885FAHD1 2443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.