Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5362087 | 0.88 | AR (0.60) | ARCYP11B2CCNCCDK8CHEK1 | |
| SCHEMBL5373726 | 0.82 | AR (0.61) | ARCCNCCDK8CHEK1GRIA2 | |
| SCHEMBL5361524 | 0.81 | AR (0.54) | ARCYP11B2CCNCCDK8CHEK1 | |
| SCHEMBL14348166 | 0.81 | AR (0.50) | ARCYP11B2CCNCCDK8CHEK1 | |
| SCHEMBL5362232 | 0.80 | AR (0.61) | ARCYP11B2CCNCCDK8GRIA2 | |
| SCHEMBL5359879 | 0.79 | AR (0.52) | ARFNTAFNTB | |
| SCHEMBL14348310 | 0.78 | AR (0.53) | ARCCNCCDK8CHEK1GRIA2 | |
| SCHEMBL4919002 | 0.77 | AR (0.70) | ARCYP11B2FNTAFNTB | |
| SCHEMBL5370036 | 0.77 | AR (0.49) | ARFNTAFNTB | |
| SCHEMBL14347768 | 0.76 | AR (0.57) | ARCYP11B2CCNCCDK8GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |