Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | OGG1 | O15527 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10944396 | 0.71 | HSD17B10 (0.37) | KMT2AHSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL1614613 | 0.71 | KDM4E (0.72) | KMT2AHSD17B10KDM4EHTTMEN1 | |
| SCHEMBL20792941 | 0.71 | KMT2A (0.48) | KMT2AHSD17B10KDM4EHTTMEN1 | |
| SCHEMBL3147406 | 0.71 | KDM4E (0.39) | KMT2AHSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL6001561 | 0.70 | ALDH1A1 (0.38) | KMT2AHSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL15977056 | 0.69 | HTT (0.50) | KMT2AKDM4EHTTMEN1ALDH1A1 | |
| SCHEMBL7140950 | 0.69 | EGFR (0.41) | KDM4EMAPT | |
| SCHEMBL7142680 | 0.69 | KDM4E (0.41) | KMT2AHSD17B10KDM4EHTTMEN1 | |
| SCHEMBL649403 | 0.68 | ALDH1A1 (0.41) | KMT2AHSD17B10KDM4EHTTMEN1 | |
| SCHEMBL6013736 | 0.68 | HSD17B10 (0.33) | KMT2AHSD17B10KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537539-A1 | 2-(2-Benzoxazolyl-oxy)acetamides and their use as herbicides | BAYER AG (DE) | 1993-04-21 | — | — | EP | claimed |