Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 8/20 | 0.54 |
| ▸ | CACNA2D1 | P54289 | 6/20 | 0.54 |
| ▸ | CACNB1 | Q02641 | 6/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.54 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.49 |
| ▸ | GPX4 | P36969 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | GHSR | Q92847 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360644 | 0.90 | CACNA1G (0.60) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL5361404 | 0.84 | CACNA2D1 (0.55) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL5359764 | 0.79 | CACNA1G (0.56) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL5356602 | 0.78 | CACNA1G (0.54) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL3320505 | 0.73 | CACNA2D1 (0.60) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL4779236 | 0.72 | DPP8 (0.63) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL5325048 | 0.72 | CACNA1G (0.60) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL5265406 | 0.72 | CACNA2D1 (1.00) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL5266301 | 0.72 | CACNA2D1 (1.00) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL5268519 | 0.72 | CACNA2D1 (1.00) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007142431-A1 | NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-12-13 | — | — | WO | claimed |
| WO-2007142431-A1 | NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-12-13 | — | — | WO | disclosed |