Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 13/20 | 0.63 |
| ▸ | ITK | Q08881 | 6/20 | 0.58 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1467481 | 0.88 | ADORA2A (0.80) | ADORA2AITKEHMT2 | |
| SCHEMBL5369293 | 0.88 | ADORA2A (0.82) | ADORA2AITK | |
| SCHEMBL1468329 | 0.80 | ADORA2A (0.89) | ADORA2AITK | |
| SCHEMBL1467861 | 0.78 | ADORA2A (1.00) | ADORA2AITK | |
| SCHEMBL12744837 | 0.76 | ADORA2A (1.00) | ADORA2AITK | |
| SCHEMBL16463988 | 0.76 | EHMT2 (0.77) | ITKEHMT2 | |
| SCHEMBL4589978 | 0.76 | ADORA2A (0.85) | ADORA2A | |
| SCHEMBL20096722 | 0.76 | OPRK1 (0.58) | EHMT2 | |
| SCHEMBL1467419 | 0.76 | ADORA2A (0.81) | ADORA2AITK | |
| SCHEMBL8225590 | 0.75 | EHMT2 (0.66) | ADORA2AITKEHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007133983-A2 | 2-AMINOBENZIMIDAZOLES FOR TREATING NEURODEGENERATIVE DISEASES | PHARMACOPEIA, INC. (US) | 2007-11-22 | — | — | WO | disclosed |