Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL27280635 | 0.87 | TDP1 (0.50) | TDP1TSHRHSD17B10MAPK1ALDH1A1 | |
| Glycerin SCHEMBL4248130 | 0.86 | LMNA (0.50) | TDP1TSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL483498 | 0.85 | — | — | |
| Isopropyl Alcohol SCHEMBL7592214 | 0.84 | ALDH1A1 (0.43) | TDP1TSHRHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL117539 | 0.83 | USP2 (0.48) | TDP1TSHRHSD17B10MAPK1ALDH1A1 | |
| Propylene Glycol SCHEMBL27876038 | 0.83 | HSD17B10 (0.67) | TDP1TSHRHSD17B10MAPK1L3MBTL1 | |
| Alcohol SCHEMBL5571921 | 0.81 | TSHR (0.41) | TDP1TSHRHSD17B10ALDH1A1L3MBTL1 | |
| Ethylene Glycol SCHEMBL351864 | 0.81 | TSHR (0.41) | TDP1TSHRHSD17B10MAPK1ALDH1A1 | |
| Methyl Alcohol SCHEMBL28414164 | 0.81 | ALDH1A1 (0.38) | TSHRHSD17B10MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL24856 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 459 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4473118-A1 | RECOMBINATION-BASED DNA ASSEMBLY METHODS AND COMPOSITIONS | Integrated DNA Technologies, Inc. (US) | 2024-12-11 | — | — | EP | claimed |
| CN-119032178-A | Recombinant-based DNA assembly methods and compositions | 合成DNA技术公司 | 2024-11-26 | — | — | CN | claimed |
| US-20230257790-A1 | RECOMBINATION-BASED DNA ASSEMBLY METHODS AND COMPOSITIONS | INTEGRATED DNA TECHNOLOGIES, INC. | 2023-08-17 | — | — | US | claimed |
| WO-2023147547-A1 | RECOMBINATION-BASED DNA ASSEMBLY METHODS AND COMPOSITIONS | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2023-08-03 | — | — | WO | claimed |
| US-11083192-B2 | Fertilizer and agrochemical formulation | MITSUI CHEMICALS AGRO, INC. (JP) | 2021-08-10 | — | — | US | claimed |
| US-20190320651-A1 | FERTILIZER AND AGROCHEMICAL FORMULATION | MITSUI CHEMICALS AGRO, INC. (JP) | 2019-10-24 | — | — | US | claimed |
| CN-110144139-A | A kind of zinc oxide base nano particle ink and photoelectric device | 纳晶科技股份有限公司 | 2019-08-20 | — | — | CN | claimed |
| US-10375951-B2 | Fertilizer and agrochemical formulation | MITSUI CHEMICALS AGRO, INC. (JP) | 2019-08-13 | — | — | US | claimed |
| CN-106564318-B | A kind of environment-friendly type exempts from alcohol edition-0 moistening liquid | 上海数印网络科技股份有限公司 | 2019-05-31 | — | — | CN | claimed |
| US-20180139954-A1 | FERTILIZER AND AGROCHEMICAL FORMULATION | MITSUI CHEMICALS AGRO, INC. (JP) | 2018-05-24 | — | — | US | claimed |
| US-5207876-A | Ketone, ether or ester extraction agents | Berg, Lloyd (US) | 1993-05-04 | — | — | US | claimed |
| US-5196094-A | Separation of 1,1,1-trichloroethane from the lower alcohols by extractive distillation | Berg, Lloyd (US) | 1993-03-23 | — | — | US | claimed |
| EP-0532185-A2 | Bleed alleviation using zwitterionic surfactants and cationic dyes | Hewlett-Packard Company (US) | 1993-03-17 | — | — | EP | claimed |
| US-5160585-A | Separation of tetrachloroethylene from a butyl alcohol by extractive distillation | Berg, Lloyd (US) | 1992-11-03 | — | — | US | claimed |
| EP-0509688-A1 | Bleed alleviation in ink-jet inks | Hewlett-Packard Company (US) | 1992-10-21 | — | — | EP | claimed |
| US-5116409-A | Bleed alleviation in ink-jet inks | HEWLETT-PACKARD COMPANY (US) | 1992-05-26 | — | — | US | claimed |
| US-5106416-A | Using concentration of surfactant at which micelles form and attract dye molecules | HEWLETT-PACKARD COMPANY (US) | 1992-04-21 | — | — | US | claimed |
| US-5085739-A | Recovering from mixture in the presence of an extractive agent | Berg, Lloyd (US) | 1992-02-04 | — | — | US | claimed |
| US-4999213-A | Polyurethane coatings for automobiles | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-03-12 | — | — | US | claimed |
| US-4935102-A | Separation of 2,3-butanediol from propylene glycol by azeotropic distillation | Berg, Lloyd (US) | 1990-06-19 | — | — | US | claimed |