Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 2/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 7/20 | 0.52 |
| ▸ | MAOB | P27338 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18215318 | 0.80 | ALOX5 (0.72) | XIAPALOX5GSTO1ALDH1A1HSD17B10 | |
| SCHEMBL4459460 | 0.77 | ALOX5 (0.56) | XIAPALOX5GSTO1ALDH1A1HSD17B10 | |
| SCHEMBL4459465 | 0.77 | ALOX5 (0.56) | XIAPALOX5GSTO1ALDH1A1HSD17B10 | |
| SCHEMBL10810440 | 0.77 | ALOX5 (0.76) | XIAPALOX5GSTO1ALDH1A1HSD17B10 | |
| SCHEMBL23604932 | 0.76 | XIAP (0.68) | XIAPALOX5GSTO1ALDH1A1HSD17B10 | |
| SCHEMBL15086878 | 0.76 | ALOX5 (0.74) | XIAPALOX5GSTO1ALDH1A1HSD17B10 | |
| SCHEMBL4459618 | 0.75 | ALOX5 (0.54) | XIAPALOX5GSTO1ALDH1A1HSD17B10 | |
| SCHEMBL4459625 | 0.75 | ALOX5 (0.54) | XIAPALOX5GSTO1ALDH1A1HSD17B10 | |
| SCHEMBL5360082 | 0.75 | ALOX5 (0.56) | XIAPALOX5GSTO1ALDH1A1HSD17B10 | |
| SCHEMBL25327043 | 0.75 | MAOA (0.60) | XIAPALOX5GSTO1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307095-B2 | Osteoporosis; antiarthritic agents; antidiabetic agents; antiinflammatory agents; Alzheimer's disease; shock; central nervous stsrem disorders; anticancer agents; multiple sclerosis, (S)-2-(Benzooxazol-2-ylamino)-3-cyclohexyl-N-[2-(5-fluoro-2,3-dihydro-indol-1-yl)-ethyl]-propionamide | IRM LLC (BM) | 2007-12-11 | — | — | US | disclosed |