SCHEMBL5360150

SCHEMBL5360150

OC(CCSc1ccc2ccccc2c1)CSc1ccc2ccccc2c1

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 12/20 0.62
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
ANPEP P15144 1/20 0.44
CAPN1 P07384 1/20 0.43
CTSB P07858 1/20 0.43
CNR2 P34972 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27611903 0.81 BACE1 (0.58) BACE1CYP3A4CYP2C9CYP2C19ANPEP
SCHEMBL20088011 0.81 BACE1 (0.58) BACE1CYP3A4CYP2C9CYP2C19ANPEP
SCHEMBL7765147 0.79 BACE1 (0.57) BACE1CYP3A4CYP2C9CYP2C19ANPEP
SCHEMBL9770073 0.78 BACE1 (0.56) BACE1CYP3A4CYP2C9CYP2C19ANPEP
SCHEMBL29738643 0.78 BACE1 (0.56) BACE1CYP3A4CYP2C9CYP2C19ANPEP
SCHEMBL5950881 0.78 BACE1 (0.52) BACE1CYP3A4CYP2C9CYP2C19ANPEP
SCHEMBL5950448 0.78 BACE1 (0.52) BACE1CYP3A4CYP2C9CYP2C19ANPEP
SCHEMBL5950452 0.78 BACE1 (0.52) BACE1CYP3A4CYP2C9CYP2C19ANPEP
SCHEMBL8479651 0.75 BACE1 (0.50) BACE1CYP3A4CYP2C9CYP2C19
SCHEMBL3894693 0.74 ANPEP (0.51) BACE1CYP3A4CYP2C9CYP2C19ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7282322-B2 Long-term high temperature and humidity stable holographic optical data storage media compositions with exceptional high dynamic range ACADIA WOODS PARTNERS, LLC 2007-10-16 US disclosed
US-7229741-B2 Exceptional high reflective index photoactive compound for optical applications INPHASE TECHNOLOGIES, INC. (US) 2007-06-12 US disclosed
EP-1508144-B1 HOLOGRAPHIC DATA STORAGE MEDIA COMPRISING AN ALUMINUM SALT COMPOUND AND AN ASYMMETRIC ACRYLATE COMPOUND INPHASE TECH INC (US) 2006-06-21 EP disclosed
US-20050259303-A1 Long-term high temperature and humidity stable holographic optical data storage media compositions with exceptional high dynamic range ACADIA WOODS PARTNERS, LLC 2005-11-24 US disclosed
EP-1508144-A1 HOLOGRAPHIC DATA STORAGE MEDIA COMPRISING AN ALUMINUM SALT COMPOUND AND AN ASYMMETRIC ACRYLATE COMPOUND InPhase Technologies, Inc. (US) 2005-02-23 EP disclosed
WO-2003102959-A1 HOLOGRAPHIC DATA STORAGE MEDIA COMPRISING AN ALUMINUM SALT COMPOUND AND AN ASYMETRIC ACRYLATE COMPOUND INPHASE TECHNOLOGIES, INC. (US) 2003-12-11 WO disclosed
WO-2003102693-A1 HIGH REFLECTIVE INDEX PHOTOACTIVE COMPOUND FOR OPTICAL APPLICATIONS INPHASE TECHNOLOGIES, INC. (US) 2003-12-11 WO disclosed
US-20030224250-A1 Novel exceptional high reflective index photoactive compound for optical applications ACADIA WOODS PARTNERS, LLC 2003-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030224250-A1 Novel exceptional high reflective index photoactive compound for optical applications ACR, DSTYK, UTS2R BACE1 4432/4885CYP3A4 4172/4885CYP2C9 4006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.