Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 3/20 | 0.32 |
| ▸ | FAAH | O00519 | 5/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 3/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pivalate SCHEMBL1831109 | 0.84 | TSHR (0.33) | CHRM2CHRM1CHRM3MAPTALDH1A1 | |
| Bicarbonate SCHEMBL27506741 | 0.83 | FFAR3 (0.35) | CHRM1CHRM3 | |
| Acetic Acid SCHEMBL1033681 | 0.80 | FFAR3 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Carbamic Acid SCHEMBL28872525 | 0.78 | ACHE (0.37) | — | |
| Propionic Acid SCHEMBL27829635 | 0.78 | FFAR3 (0.53) | ALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL628113 | 0.77 | EPHX1 (0.31) | ALDH1A1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL3708677 | 0.75 | MLYCD (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Trifluoroacetic Acid SCHEMBL17396033 | 0.75 | CHRM2 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Trifluoroacetic Acid SCHEMBL726303 | 0.75 | MLYCD (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Trifluoroacetic Acid SCHEMBL3708678 | 0.75 | MLYCD (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100379709-C | Process for preparing phosphitylated compounds | HONEYWELL INT INC (US) | 2008-04-09 | — | — | CN | claimed |
| CN-1646452-A | Process for preparing phosphitylated compounds | HONEYWELL INT INC (US) | 2005-07-27 | — | — | CN | claimed |
| US-6894158-B2 | Methods of producing phosphitylated compounds | HONEYWELL INTERNATIONAL INC. (US) | 2005-05-17 | — | — | US | claimed |
| EP-1476407-A2 | METHODS OF PRODUCING PHOSPHITYLATED COMPOUNDS | Honeywell International Inc. (US) | 2004-11-17 | — | — | EP | claimed |
| US-20030232980-A1 | Methods of producing phosphitylated compounds | HONEYWELL INTERNATIONAL INC. | 2003-12-18 | — | — | US | claimed |
| WO-2003072586-A2 | METHODS OF PRODUCING PHOSPHITYLATED COMPOUNDS | HONEYWELL INTERNATIONAL INC. (US) | 2003-09-04 | — | — | WO | claimed |
| CN-108472381-B | Compounds and therapeutic uses thereof | 森陶里治疗有限公司 | 2023-06-06 | — | — | CN | disclosed |
| US-20210369850-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | Centauri Therapeutics Limited (GB/GB) (GB) | 2021-12-02 | — | — | US | disclosed |
| US-10953100-B2 | Compounds and therapeutic uses thereof | CENTUARI THERAPEUTICS LIMITED (GB/GB) (GB) | 2021-03-23 | — | — | US | disclosed |
| US-20180280521-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | CENTUARI THERAPEUTICS LIMITED (GB/GB) (GB) | 2018-10-04 | — | — | US | disclosed |
| CN-108472381-A | COMPOUNDS AND THERAPEUTIC USES THEREOF | 森陶里治疗有限公司 | 2018-08-31 | — | — | CN | disclosed |
| WO-2017060729-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | CENTAURI THERAPEUTICS LIMITED (GB) | 2017-04-13 | — | — | WO | disclosed |
| EP-2864308-B1 | (3aR,6aS)-2-Hydroxy-3,3a,6,6a-tetrahydro-2H-cyclopenta[b]furan-5-carbaldehyde intermediates for the preparation of prostaglandins or prostaglandin analogues | UNIV BRISTOL (GB) | 2016-10-19 | — | — | EP | disclosed |
| US-20030232980-A1 | Methods of producing phosphitylated compounds | HONEYWELL INTERNATIONAL INC. | 2003-12-18 | — | — | US | disclosed |
| WO-2003072586-A2 | METHODS OF PRODUCING PHOSPHITYLATED COMPOUNDS | HONEYWELL INTERNATIONAL INC. (US) | 2003-09-04 | — | — | WO | disclosed |
| EP-0882041-B1 | PIPERAZINONEPHENYLOXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2003-03-26 | — | — | EP | disclosed |
| US-6069145-A | AGAINST ANTIBIOTIC RESISTANT BACTERIA | ZENECA LIMITED (GB) | 2000-05-30 | — | — | US | disclosed |
| EP-0882041-A1 | PIPERAZINONEPHENYLOXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | AstraZeneca AB (SE) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997027188-A1 | PIPERAZINONEPHENYLOXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ZENECA LIMITED (GB) | 1997-07-31 | — | — | WO | disclosed |
| US-3944538-A | Process and apparatus for the synthesis of peptides not linked to polymers | BODANSZKY MIKLOS | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210369850-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | CD47, MYD88, NFATC1 | CHRM2 4527/4885CHRM4 4479/4885CHRM5 4402/4885 |
| US-10953100-B2 | Compounds and therapeutic uses thereof | CD47, MYD88, NFATC1 | CHRM2 4527/4885CHRM4 4479/4885CHRM5 4402/4885 |
| US-20180280521-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | CD47, MYD88, NFATC1 | CHRM2 4527/4885CHRM4 4479/4885CHRM5 4402/4885 |
| US-20030232980-A1 | Methods of producing phosphitylated compounds | PHOSPHO1, INPPL1, PLCG1 | CHRM2 2495/4885CHRM4 2806/4885CHRM5 2326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.