Sugi Predict

Sugi Predict / Compounds / SCHEMBL5360429

SCHEMBL5360429

SCHEMBL5360429

Cn1nc(C(C2CCNCC2)N2C(=O)CN(S(=O)(=O)c3ccc4cc(Cl)ccc4c3)C[C@@H]2C(=O)O)ccc1=O

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 20/20 0.38
▸ F2 P00734 8/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4938813 1.00 F10 (0.38) F10F2
SCHEMBL4939375 0.92 F10 (0.39) F10F2
SCHEMBL4936205 0.88 F10 (0.48) F10
SCHEMBL4883307 0.86 GAA (0.32) F10F2
SCHEMBL4938570 0.80 F10 (0.48) F10
SCHEMBL4934903 0.80 PPARG (0.34) F10
SCHEMBL4891921 0.78 ALDH1A1 (0.31) —
SCHEMBL4881821 0.78 ALDH1A1 (0.33) F10
SCHEMBL5326463 0.77 F10 (0.35) F10F2
SCHEMBL4939759 0.77 F10 (0.33) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007008143-A1 HETEROCYCLIC SULFONAMIDE DERIVATIVES AS INHIBITORS OF FACTOR XA ASTRAZENECA AB (SE) 2007-01-18 — — WO disclosed