Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4883307 | 0.91 | GAA (0.32) | F10F2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4881821 | 0.91 | ALDH1A1 (0.33) | F10ALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL4891921 | 0.91 | ALDH1A1 (0.31) | ALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL4893938 | 0.88 | CASP3 (0.31) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5328237 | 0.78 | MEN1 (0.31) | KMT2A | |
| SCHEMBL4883075 | 0.78 | F10 (0.36) | F10F2ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL4894919 | 0.78 | F10 (0.36) | F10F2ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL4894977 | 0.78 | F10 (0.36) | F10F2ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL5360429 | 0.77 | F10 (0.38) | F10F2 | |
| SCHEMBL4938813 | 0.77 | F10 (0.38) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008146-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS INHIBITORS OF FACTOR XA | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | claimed |