Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL48876 | 0.88 | — | — | |
| Urea SCHEMBL4300101 | 0.88 | ALDH1A1 (0.60) | LMNAALDH1A1TDP1OR51E2ALOX15 | |
| Urea SCHEMBL4625226 | 0.88 | ALDH1A1 (0.60) | LMNAALDH1A1TDP1OR51E2ALOX15 | |
| Guanidine SCHEMBL3856351 | 0.88 | — | — | |
| Guanidine SCHEMBL9640861 | 0.83 | LMNA (0.67) | LMNAALDH1A1TDP1OR51E2ALOX15 | |
| Guanidine SCHEMBL1639599 | 0.83 | — | — | |
| Urea SCHEMBL16166219 | 0.80 | — | — | |
| Urea SCHEMBL4967133 | 0.80 | — | — | |
| Urea SCHEMBL759609 | 0.80 | — | — | |
| Guanidine SCHEMBL27827658 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205046-B2 | Electrophotographic lamination film, a method of producing the same, and a method of forming an image | FUJI XEROX CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |
| US-6723444-B2 | YMAGE-RECEIVING LAYER IS DISPOSED ON ONE SIDE OF A TRANSPARENT SUBSTRATE, AND A REVERSE IMAGE (MIRROR IMAGE) IS FORMED SUCH THAT WHEN THE IMAGE IS VIEWED THROUGH THE SUBSTRATE, THE IMAGE IS SEEN AS A NORMAL ROTATION IMAGE | FUJI XEROX CO., LTD. (JP) | 2004-04-20 | — | — | US | disclosed |
| US-20030232275-A1 | Image recording material and image display material using the same | FUJI XEROX CO., LTD. (JP) | 2003-12-18 | — | — | US | disclosed |
| EP-1369747-A2 | Electrophotographic lamination film, a method of producing the same, and a method of forming an image | FUJI XEROX CO., LTD. (JP) | 2003-12-10 | — | — | EP | disclosed |
| US-20030224169-A1 | Electrophotographic lamination film, a method of producing the same, and a method of forming an image | FUJI XEROX CO., LTD. (JP) | 2003-12-04 | — | — | US | disclosed |