SCHEMBL5360974

SCHEMBL5360974

CNC(=O)C1CC2C=CC1C2

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.69
LMNA P02545 1/20 0.69
THRB P10828 1/20 0.48
ALDH1A1 P00352 5/20 0.40
EPHX2 P34913 3/20 0.38
HPGD P15428 1/20 0.37
KMT2A Q03164 2/20 0.36
POLB P06746 2/20 0.36
RAB9A P51151 2/20 0.36
TDP1 Q9NUW8 2/20 0.35
GAA P10253 1/20 0.35
NPC1 O15118 1/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
APEX1 P27695 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
ESR2 Q92731 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24213868 0.82 KDM4E (1.00) KDM4ELMNATHRBALDH1A1EPHX2
SCHEMBL26031926 0.80 KDM4E (0.69) KDM4ELMNATHRBALDH1A1EPHX2
SCHEMBL5366429 0.79 KDM4E (0.62) KDM4ELMNATHRBALDH1A1EPHX2
SCHEMBL5349832 0.79 KDM4E (0.62) KDM4ELMNATHRBALDH1A1EPHX2
SCHEMBL24220248 0.79 LMNA (0.62) KDM4ELMNATHRBALDH1A1EPHX2
SCHEMBL780067 0.79 KDM4E (0.62) KDM4ELMNATHRBALDH1A1EPHX2
SCHEMBL5360459 0.78 KDM4E (0.61) KDM4ELMNATHRBALDH1A1EPHX2
SCHEMBL6137154 0.77 KDM4E (0.65) KDM4ELMNATHRBALDH1A1EPHX2
SCHEMBL11689296 0.77 KDM4E (0.59) KDM4ELMNATHRBALDH1A1EPHX2
SCHEMBL14822849 0.77 KDM4E (0.59) KDM4ELMNATHRBALDH1A1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4039491-A IMPACT STRENGTH, NORBORNENE DERIVATIVE CONTAINING POLAR GROUP JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1977-08-02 US claimed
EP-4617314-A1 COMPOSITION FOR FORMING A MOLDED PRODUCT HAVING LOW DIELECTRIC LOSS, METHOD FOR FORMING A MOLDED PRODUCT, AND MOLDED PRODUCT HAVING LOW DIELECTRIC LOSS Daikin Industries, Ltd. (JP) 2025-09-17 EP disclosed
US-20200390777-A1 LIPID PRODRUGS OF MYCOPHENOLIC ACID AND USES THEREOF SEAPORT THERAPEUTICS, INC. 2020-12-17 US disclosed
EP-3669978-A1 BI-FUNCTIONAL NANOHYBRIDS Université de Bourgogne (FR) 2020-06-24 EP disclosed
US-10329383-B2 Cyanate resin blends and radomes including them SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2019-06-25 US disclosed
US-20190112406-A1 Resins and Radomes Including Them SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION 2019-04-18 US disclosed
US-20180258223-A1 CYANATE RESIN BLENDS AND RADOMES INCLUDING THEM SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION 2018-09-13 US disclosed
WO-2018151800-A2 RADOME FABRICATION USING CYCLIC OLEFIN RESIN IN LIQUID MOLDING SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2018-08-23 WO disclosed
US-9914803-B2 Cyanate resin blends and radomes including them SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2018-03-13 US disclosed
EP-3013869-A1 RESINS AND RADOMES INCLUDING THEM Saint-gobain Performance Plastics Corporation (US) 2016-05-04 EP disclosed
US-5053471-A Methathesis ring opening polymerization of polar substituted norbornenes or octahydromethanonphthalenes; optics JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-10-01 US disclosed
EP-0409291-A2 Thermoplastic resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-01-23 EP disclosed
US-4980421-A Dicyclopentadienyltitanium compounds, lithium compounds and reducing agents containing aluminum, zinc or magnesium; efficiency JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-12-25 US disclosed
EP-0339986-A1 Novel catalyst for hydrogenation of polymer and process for hydrogenating polymer with the catalyst JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1989-11-02 EP disclosed
EP-0317262-A2 Transparent resin material JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1989-05-24 EP disclosed
US-4250063-A COORDINATION CATALYST COMPRISING AN ORGANIC COMPLEX OF TUNGSTEN OR MOLYBDENUM, A TITANIUM TETRAHALIDE, AND AN N-HALO IMIDE, A SULFIDE, A SULFOXIDE, OR A PHOSPHINE; POLYALKENAMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-02-10 US disclosed
US-4176220-A COORDINATION CATALYST JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1979-11-27 US disclosed
US-4106943-A RING-OPENED POLYMER OR COPOLYMER OF NORBORNENE DERIVATIVE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1978-08-15 US disclosed
US-4068063-A Catalyst composition for ring-opening polymerization of norbornene derivatives and process for polymerizing same JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1978-01-10 US disclosed
US-4039491-A IMPACT STRENGTH, NORBORNENE DERIVATIVE CONTAINING POLAR GROUP JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1977-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200390777-A1 LIPID PRODRUGS OF MYCOPHENOLIC ACID AND USES THEREOF MALT1, CYP2B6, LIPA KDM4E 1491/4885LMNA 4002/4885THRB 3604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.