Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CCR1 | P32246 | 3/20 | 0.52 |
| ▸ | CCR5 | P51681 | 3/20 | 0.52 |
| ▸ | CCR8 | P51685 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | ALPI | P09923 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27707985 | 0.83 | KDM4E (0.52) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL3567699 | 0.81 | CCR1 (0.53) | KDM4ECCR1CCR8ALDH1A1HPGD | |
| SCHEMBL4447801 | 0.81 | BPTF (0.54) | KDM4ELMNASMN1; SMN2TP53HTT | |
| SCHEMBL5022939 | 0.78 | CCR1 (0.44) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL3575717 | 0.77 | BPTF (0.43) | KDM4ELMNASMN1; SMN2HTTTDP1 | |
| SCHEMBL30122726 | 0.76 | SDHB (0.47) | KDM4ELMNASMN1; SMN2TP53HTT | |
| SCHEMBL1264511 | 0.76 | BPTF (0.42) | KDM4ELMNASMN1; SMN2TDP1BLM | |
| Dipyridyl SCHEMBL27645628 | 0.75 | KDM4E (0.64) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL24774090 | 0.75 | DYRK1A (0.35) | KDM4ELMNASMN1; SMN2TP53HTT | |
| SCHEMBL24774281 | 0.75 | PTGS2 (0.39) | KDM4ELMNASMN1; SMN2TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238697-B2 | Pyridylpyrimidines for use as pesticides | BAYER CROPSCIENCE AG (DE) | 2007-07-03 | — | — | US | disclosed |
| US-7238697-B2 | Pyridylpyrimidines for use as pesticides | BAYER CROPSCIENCE AG (DE) | 2007-07-03 | — | — | US | disclosed |
| US-7238697-B2 | Pyridylpyrimidines for use as pesticides | BAYER CROPSCIENCE AG (DE) | 2007-07-03 | — | — | US | disclosed |
| US-20040077641-A1 | Pyridyl pyrimidines for use as pesticides | BAYER CROPSCIENCE AG (DE) | 2004-04-22 | — | — | US | disclosed |
| EP-1367893-A1 | PYRIDYL PYRIMIDINES FOR USE AS PESTICIDES | Bayer CropScience AG (DE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002067684-A1 | PYRIDYL PYRIMIDINES FOR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2002-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077641-A1 | Pyridyl pyrimidines for use as pesticides | PNPO, P2RX6, P2RX1 | KDM4E 2707/4885LMNA 3538/4885CCR1 396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.