Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 14/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 6/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804302 | 0.89 | TDP1 (0.50) | CA1CA2CA7CYP2D6TDP1 | |
| SCHEMBL1251053 | 0.87 | TDP1 (0.53) | CA1CA2CA7CYP2D6TDP1 | |
| SCHEMBL1843190 | 0.85 | CTSK (0.53) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL4759889 | 0.84 | CA1 (0.50) | CA1CA2CA7CYP2D6TDP1 | |
| SCHEMBL13306565 | 0.84 | CA1 (0.50) | CA1CA2CA7CYP2D6TDP1 | |
| SCHEMBL3735437 | 0.82 | CA1 (0.49) | CA1CA2CA7CYP2D6TDP1 | |
| SCHEMBL10960987 | 0.81 | MEN1 (0.56) | CA1CA2CA7CYP2D6TDP1 | |
| SCHEMBL628885 | 0.81 | CTSK (0.57) | CTSKCTSS | |
| SCHEMBL7119554 | 0.81 | CA1 (0.49) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL2389101 | 0.81 | CA1 (0.51) | CA1CA2CA7CYP2D6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106750331-B | High-adsorbability polyester material and preparation method thereof | 东华大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-107759779-B | Antibacterial polyester material and preparation method thereof | 东华大学 | 2020-04-07 | — | — | CN | disclosed |
| US-7223833-B1 | Peptide nucleic acid conjugates | ISIS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| EP-0804456-B1 | PEPTIDE NUCLEIC ACID CONJUGATES | ISIS PHARMACEUTICALS INC (US) | 2002-08-21 | — | — | EP | disclosed |
| EP-0835238-B1 | NEW CATIONIC AND POLYCATIONIC AMPHIPHILES, REACTIVES CONTAINING THE SAME AND THEIR USE | ROCHE DIAGNOSTICS GMBH (DE) | 2001-02-21 | — | — | EP | disclosed |
| WO-2000064904-A1 | 5,7-BICYCLIC AMIDINE DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2000-11-02 | — | — | WO | disclosed |
| US-6060455-A | AGGREGATION WITH RNA OR DNA; DELIVERY INTO CELLS | BOEHRINGER MANNHEIM GMBH (DE) | 2000-05-09 | — | — | US | disclosed |
| EP-0804456-A4 | PEPTIDE NUCLEIC ACID CONJUGATES | ISIS PHARMACEUTICALS INC (US) | 1999-05-19 | — | — | EP | disclosed |
| CN-1193316-A | Novel cationic and polycationic amphiphiles, agents containing same and use thereof | MANNHEIM BOEHRINGER GMBH (DE) | 1998-09-16 | — | — | CN | disclosed |
| EP-0804456-A1 | PEPTIDE NUCLEIC ACID CONJUGATES | ISIS PHARMACEUTICALS, INC. (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996011205-A9 | PEPTIDE NUCLEIC ACID CONJUGATES | — | 1996-05-30 | — | — | WO | disclosed |
| WO-1996011205-A1 | PEPTIDE NUCLEIC ACID CONJUGATES | ISIS PHARMACEUTICALS, INC. (US) | 1996-04-18 | — | — | WO | disclosed |