SCHEMBL7804302

SCHEMBL7804302

CC(C)(C)OC(=O)NC(O)CCCO

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.50
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
CYP2D6 P10635 1/20 0.44
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
GAA P10253 1/20 0.44
CTSK P43235 14/20 0.43
CTSS P25774 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1251053 0.95 TDP1 (0.53) TDP1CA1CA2CA7CYP2D6
SCHEMBL5361335 0.89 CA1 (0.47) TDP1CA1CA2CA7CYP2D6
SCHEMBL628885 0.86 CTSK (0.57) CTSKCTSS
SCHEMBL28922540 0.84 TDP1 (0.43) TDP1CA1CA2CA7CYP2D6
SCHEMBL2239345 0.84 CTSK (0.52) CTSKCTSS
SCHEMBL27490793 0.83 MEN1 (0.45) CA1CA2CA7CYP2D6KMT2A
SCHEMBL5133847 0.83 CTSK (0.51) CTSKCTSS
SCHEMBL5033253 0.83 CYP2D6 (0.49) CA1CA2CA7CYP2D6KMT2A
SCHEMBL24687980 0.82 TDP1 (0.50) TDP1CA1CA2CA7CYP2D6
SCHEMBL361540 0.82 TDP1 (0.50) TDP1CA1CA2CA7CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106750331-B High-adsorbability polyester material and preparation method thereof 东华大学 2020-08-11 CN disclosed
CN-107759779-B Antibacterial polyester material and preparation method thereof 东华大学 2020-04-07 CN disclosed
EP-0610958-B1 Intermediates in the preparation of 4-oxoquinoline-3-carboxylic acid derivatives UBE INDUSTRIES (JP) 2001-10-04 EP disclosed
EP-0644873-B1 ORNITHINE DECARBOXYLASE INHIBITING BRANCHED AMINOOXY AMINO ALKANE DERIVATIVES CIBA GEIGY AG (CH) 1997-03-12 EP disclosed
US-5610195-A ANTITUMOR AGENTS CIBA-GEIGY CORPORATION (US) 1997-03-11 US disclosed
US-5496951-A 1-CYCLOPROPYL-6-FLUORO-8-FLUORINATED METHOXY COMPOUNDS INCLUDING BORON DIFLUORIDE CHELATE; CHEMICAL INTERMEDIATES AND ANTIBACTERIAL AGENTS SANKYO COMPANY, LIMITED (JP) 1996-03-05 US disclosed
US-5436367-A 3, 4-difluorobenzoic acid derivatives SANKO COMPANY, LIMITED (JP) 1995-07-25 US disclosed
EP-0352123-B1 4-Oxoquinoline-3-carboxylic acid derivatives, their preparation and their use UBE INDUSTRIES (JP) 1995-01-18 EP disclosed
US-5348961-A Antibacterial agents SANKYO COMPANY LIMITED (JP) 1994-09-20 US disclosed
EP-0610958-A2 Intermediates in the preparation of 4-oxoquinoline-3-carboxylic acid derivatives UBE INDUSTRIES, LTD. (JP) 1994-08-17 EP disclosed
US-5073556-A Bactericides SANKYO COMPANY LIMITED (JP) 1991-12-17 US disclosed
EP-0352123-A2 4-Oxoquinoline-3-carboxylic acid derivatives, their preparation and their use UBE INDUSTRIES LIMITED (JP) 1990-01-24 EP disclosed