SCHEMBL536157

SCHEMBL536157

COC(C(=O)OCCC(C)C)=C(OC)c1ccccc1OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.46
ALDH1A1 P00352 3/20 0.45
KDM4E B2RXH2 2/20 0.45
HSD17B10 Q99714 1/20 0.45
CTSD P07339 1/20 0.44
POLB P06746 1/20 0.42
HPGD P15428 3/20 0.42
KMT2A Q03164 2/20 0.42
GAA P10253 1/20 0.42
PKM P14618 1/20 0.42
NPC1 O15118 1/20 0.42
KCNA3 P22001 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
CYP19A1 P11511 1/20 0.40
TP53 P04637 1/20 0.40
GLA P06280 1/20 0.40
LMNA P02545 1/20 0.40
STAT3 P40763 1/20 0.40
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29365595 1.00 HTT (0.46) HTTALDH1A1KDM4EHSD17B10CTSD
SCHEMBL1275711 0.92 HTT (0.40) HTTALDH1A1KDM4EHSD17B10CTSD
SCHEMBL28450175 0.90 HTT (0.39) HTTALDH1A1KDM4EHSD17B10CTSD
SCHEMBL18940690 0.82 POLB (0.38) ALDH1A1CTSDPOLBHPGDKMT2A
SCHEMBL29069533 0.81 ALDH1A1 (0.52) ALDH1A1KDM4EHSD17B10CTSDPOLB
SCHEMBL9134542 0.80 CTSD (0.53) ALDH1A1HSD17B10CTSDPOLBHPGD
SCHEMBL31022703 0.80 CTSD (0.53) ALDH1A1HSD17B10CTSDPOLBHPGD
SCHEMBL18940692 0.80 POLB (0.36) ALDH1A1CTSDPOLBHPGDKMT2A
SCHEMBL30664617 0.80 HPGD (0.47) ALDH1A1CTSDHPGDKMT2ANPC1
SCHEMBL17502652 0.79 ALDH1A1 (0.56) HTTALDH1A1KDM4EHSD17B10CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250197239-A1 ZINC OXIDE POWDER, LIQUID DISPERSION, COATING MATERIAL, AND COSMETIC SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2025-06-19 US disclosed
US-20240415758-A1 COSMETIC SHISEIDO COMPANY, LTD. (JP) 2024-12-19 US disclosed
EP-4474354-A1 ZINC OXIDE POWDER, LIQUID DISPERSION, COATING MATERIAL, AND COSMETIC Sumitomo Osaka Cement Co., Ltd. (JP) 2024-12-11 EP disclosed
CN-117979961-A Stabilized compositions 鲁米兰特私人有限公司 2024-05-03 CN disclosed
WO-2023083445-A1 COMPOSITIONS COMPRISING TRPM8 AGONISTIC COOLING AGENTS SYMRISE AG (DE) 2023-05-19 WO disclosed
US-8962684-B2 Antioxidant composition SHISEIDO COMPANY, LTD. (JP) 2015-02-24 US disclosed
US-8735442-B2 Composition for alleviating ultraviolet radiation-induced damage SHISEIDO COMPANY, LTD. (JP) 2014-05-27 US disclosed
US-8637572-B2 Composition for promoting collagen production SHISEIDO COMPANY, LTD. (JP) 2014-01-28 US disclosed
EP-2516511-A2 THICKENER OR GELLANT FOR OIL MATERIALS, GEL COMPOSITION COMPRISING SAME, AND METHOD OF PRODUCING COSMETIC MATERIAL OR TOPICAL AGENT Dow Corning Toray Co., Ltd. (JP) 2012-10-31 EP disclosed
US-20120184619-A1 COMPOSITION FOR PROMOTING COLLAGEN PRODUCTION SHISEIDO COMPANY, LTD 2012-07-19 US disclosed
US-20120184620-A1 ANTIOXIDANT COMPOSITION SHISEIDO COMPANY, LTD. 2012-07-19 US disclosed
US-20120142941-A1 COMPOSITION FOR ALLEVIATING ULTRAVIOLET RADIATION-INDUCED DAMAGE SHISEIDO COMPANY, LTD. 2012-06-07 US disclosed
US-20120122951-A1 SKIN-WHITENING AGENT AND COSMETIC METHOD FOR WHITENING SKIN SHISEIDO COMPANY, LTD. 2012-05-17 US disclosed
EP-2415453-A1 SKIN-WHITENING AGENT AND COSMETIC METHOD FOR WHITENING SKIN Shiseido Company, Ltd. (JP) 2012-02-08 EP disclosed
WO-2011078395-A2 THICKENER OR GELLANT FOR OIL MATERIALS, GEL COMPOSITION COMPRISING SAME, AND METHOD OF PRODUCING COSMETIC MATERIAL OR TOPICAL AGENT DOW CORNING TORAY CO., LTD. (JP) 2011-06-30 WO disclosed
US-20090136540-A1 Anti-aging composition and collagen production promoting composition SHISEIDO COMPANY, LTD. 2009-05-28 US disclosed
US-20070134265-A1 Anti-aging composition and collagen production promoting composition SHISEIDO COMPANY, LTD. (JP) 2007-06-14 US disclosed