Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468889 | 0.77 | AR (0.86) | ARCYP11B2CYP11B1CYP19A1 | |
| SCHEMBL6465872 | 0.77 | AR (0.76) | ARCYP11B2CYP11B1CYP19A1 | |
| SCHEMBL6464131 | 0.77 | AR (0.80) | ARCYP11B2CYP11B1CYP19A1 | |
| SCHEMBL6466150 | 0.77 | AR (0.69) | ARCYP11B2CYP11B1CYP19A1 | |
| SCHEMBL6465272 | 0.76 | AR (1.00) | ARCYP11B2CYP11B1CYP19A1 | |
| SCHEMBL6469584 | 0.76 | AR (0.61) | ARCYP11B2CYP11B1CYP19A1 | |
| SCHEMBL14347633 | 0.76 | AR (0.58) | ARCYP11B2CYP19A1GRIA2GRIA4 | |
| SCHEMBL6464451 | 0.75 | AR (0.80) | ARCYP11B2CYP11B1CYP19A1 | |
| SCHEMBL5357480 | 0.75 | AR (0.61) | ARCYP11B2CYP19A1GRIA2GRIA4 | |
| SCHEMBL5362350 | 0.75 | AR (0.57) | ARCYP11B2CYP11B1GRIA2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |