Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5366328 | 0.83 | AR (0.60) | ARGRIA2GRIA4 | |
| SCHEMBL14348320 | 0.82 | AR (0.53) | ARGRIA2GRIA4 | |
| SCHEMBL5358252 | 0.81 | AR (0.52) | ARCYP11B2GRIA2GRIA4CYP11B1 | |
| SCHEMBL6468079 | 0.80 | AR (0.58) | ARCYP11B2 | |
| SCHEMBL14347633 | 0.80 | AR (0.58) | ARCYP11B2GRIA2GRIA4GAA | |
| SCHEMBL6468889 | 0.76 | AR (0.86) | ARCYP11B2PDE9APDE1CCYP11B1 | |
| SCHEMBL5361589 | 0.75 | AR (0.61) | ARCYP11B2GRIA2GRIA4CYP11B1 | |
| SCHEMBL5357480 | 0.74 | AR (0.61) | ARCYP11B2GRIA2GRIA4 | |
| SCHEMBL6465872 | 0.74 | AR (0.76) | ARCYP11B2PDE9APDE1CCYP11B1 | |
| SCHEMBL24414502 | 0.73 | AR (0.80) | ARCYP11B2PDE9APDE1CCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | claimed |
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |