Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | SDHB | P21912 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360218 | 0.83 | AR (0.53) | ARGAACYP11B2CNR1SDHB | |
| SCHEMBL5366353 | 0.77 | AR (0.60) | ARCYP11B2GRIA2GRIA4 | |
| SCHEMBL5361524 | 0.77 | AR (0.54) | ARCYP11B2KIF11 | |
| SCHEMBL5362024 | 0.76 | AR (0.58) | ARGAACYP11B2GRIA2GRIA4 | |
| SCHEMBL5365976 | 0.75 | AR (0.52) | ARGAACYP11B2GRIA2GRIA4 | |
| SCHEMBL5362158 | 0.75 | AR (0.53) | ARCYP11B2CNR1 | |
| SCHEMBL6466987 | 0.74 | AR (0.58) | ARCYP11B2GRIA2GRIA4 | |
| SCHEMBL6466733 | 0.74 | AR (0.60) | ARCYP11B2GRIA2GRIA4 | |
| SCHEMBL14347633 | 0.74 | AR (0.58) | ARGAACYP11B2GRIA2GRIA4 | |
| SCHEMBL5362232 | 0.73 | AR (0.61) | ARCYP11B2GRIA2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |