Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360218 | 0.88 | AR (0.53) | ARGAAMAPK1CYP11B2 | |
| SCHEMBL6464529 | 0.77 | AR (0.69) | ARCYP11B2KDM1A | |
| SCHEMBL5361772 | 0.75 | AR (0.53) | ARGAAGRIA2GRIA4CYP11B2 | |
| SCHEMBL5365843 | 0.75 | AR (0.58) | ARGAACYP11B2LMNAMAPT | |
| SCHEMBL14347707 | 0.74 | AR (0.58) | ARGRIA2GRIA4CYP11B2FNTA | |
| SCHEMBL6464438 | 0.72 | AR (0.73) | ARCYP11B2KDM1ASLC22A12 | |
| SCHEMBL5367267 | 0.72 | AR (0.52) | ARGRIA2GRIA4CYP11B2KDM1A | |
| SCHEMBL5362158 | 0.72 | AR (0.53) | ARCYP11B2FNTAFNTB | |
| SCHEMBL6468889 | 0.72 | AR (0.86) | ARCYP11B2KDM4E | |
| SCHEMBL14347629 | 0.71 | AR (0.43) | ARMAPK1GRIA2GRIA4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |