Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HAVCR2 | Q8TDQ0 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313691 | 0.87 | MAPT (0.45) | MAPTSMN1; SMN2HAVCR2TP53MEN1 | |
| SCHEMBL5313697 | 0.87 | MAPT (0.45) | MAPTSMN1; SMN2HAVCR2TP53MEN1 | |
| SCHEMBL5311834 | 0.85 | MAPT (0.47) | MAPTSMN1; SMN2HAVCR2TP53MEN1 | |
| SCHEMBL5311831 | 0.85 | MAPT (0.47) | MAPTSMN1; SMN2HAVCR2TP53MEN1 | |
| SCHEMBL14530969 | 0.85 | RAB9A (0.45) | MAPTSMN1; SMN2TP53MEN1KMT2A | |
| SCHEMBL5313729 | 0.85 | MAPT (0.39) | MAPTSMN1; SMN2HAVCR2TP53MEN1 | |
| SCHEMBL5313731 | 0.85 | MAPT (0.39) | MAPTSMN1; SMN2HAVCR2TP53MEN1 | |
| SCHEMBL5799421 | 0.83 | PPARG (0.50) | MAPTSMN1; SMN2TP53PPARA | |
| SCHEMBL5799336 | 0.83 | PPARG (0.50) | MAPTSMN1; SMN2TP53PPARA | |
| SCHEMBL5316159 | 0.83 | MAPT (0.41) | MAPTSMN1; SMN2HAVCR2TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |