Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12233233 | 0.92 | ADRB2 (0.50) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL12233224 | 0.91 | ADRB2 (0.49) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL24813507 | 0.88 | MAPT (0.37) | MAPTADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL21226110 | 0.88 | GABRP (0.38) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL10844633 | 0.87 | MAPT (0.35) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL10846746 | 0.87 | MAPT (0.35) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL10846749 | 0.87 | MAPT (0.35) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL10844628 | 0.87 | MAPT (0.35) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL5368697 | 0.85 | ADRB2 (0.41) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL10851120 | 0.84 | ADRB2 (0.36) | MAPTADRB2ADRB1ADRB3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208545-B1 | Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-24 | — | — | US | claimed |
| EP-1194396-B1 | SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS | BASF AG (DE) | 2005-11-09 | — | — | EP | claimed |
| US-7208545-B1 | Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-24 | — | — | US | disclosed |