Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | KLK7 | P49862 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4945237 | 0.79 | ALDH1A1 (0.40) | KMT2AMEN1HRH4ALDH1A1GAA | |
| SCHEMBL13993091 | 0.73 | NOTUM (0.46) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL5363349 | 0.73 | SPR (0.35) | SPRKMT2ANPC1TTRRAD52 | |
| SCHEMBL5366609 | 0.72 | SPR (0.45) | SPRNPC1TTRMAPTHPGD | |
| SCHEMBL5331064 | 0.72 | SPR (0.45) | SPRNPC1TTRMAPTHPGD | |
| SCHEMBL5331062 | 0.71 | SPR (0.44) | SPRKMT2AMEN1NPC1TTR | |
| SCHEMBL5334692 | 0.71 | NOTUM (0.51) | SPR | |
| SCHEMBL11714271 | 0.69 | NPC1 (0.61) | KMT2ANPC1TTRGAAMAPT | |
| SCHEMBL22868343 | 0.65 | MEN1 (0.32) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL14346538 | 0.64 | SPR (0.39) | SPRMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146230-A2 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MERCK & CO., INC. (US) | 2007-12-21 | — | — | WO | disclosed |