SCHEMBL536372

SCHEMBL536372

CC(=O)C(C(=O)O)C1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.36
GAA P10253 2/20 0.36
HTT P42858 1/20 0.35
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.33
EZH2 Q15910 1/20 0.33
KDM4E B2RXH2 1/20 0.31
KMT2A Q03164 1/20 0.31
ALOX15 P16050 1/20 0.31
RECQL P46063 1/20 0.31
CPN1 P15169 1/20 0.31
CPB2 Q96IY4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL996506 0.78 GAA (0.48) POLBGAAHTTTSHREZH2
SCHEMBL10575972 0.74 POLB (0.37) POLBGAAHTTTSHREZH2
SCHEMBL10567566 0.74 POLB (0.37) POLBGAAHTTKDM4EKMT2A
SCHEMBL29363917 0.73 POLB (0.36) POLBGAAHTTTSHREZH2
SCHEMBL19926140 0.72 CPN1 (0.33) CPN1CPB2
SCHEMBL11862121 0.72 HTT (0.37) POLBGAAHTTTSHREZH2
SCHEMBL7768598 0.72 CYP1A2 (0.37) POLBGAAHTTCPN1CPB2
SCHEMBL669633 0.70 HTT (0.39) POLBGAAHTTTSHRALDH1A1
SCHEMBL669634 0.70 HTT (0.39) POLBGAAHTTTSHRALDH1A1
Oxalic Acid SCHEMBL15635261 0.70 ALOX15 (0.42) POLBGAAHTTTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2831160-A1 STABLE COMPOSITIONS OF THIABENDAZOLE AND IODINE-CONTAINING FUNGICIDES Lanxess Deutschland GmbH (DE) 2015-02-04 EP disclosed
WO-2013144145-A1 STABLE COMPOSITIONS OF THIABENDAZOLE AND IODINE-CONTAINING FUNGICIDES LANXESS DEUTSCHLAND GMBH (DE) 2013-10-03 WO disclosed
EP-2449016-A1 POLYMERS CONTAINING HETEROCYCLIC 3-RING COMPOUNDS AND IODINE-CONTAINING COMPOUNDS Lanxess Deutschland GmbH (DE) 2012-05-09 EP disclosed
EP-2440043-A1 INORGANIC CARRIER MATERIALS CONTAINING HETEROCYCLIC 3-RING COMPOUNDS Lanxess Deutschland GmbH (DE) 2012-04-18 EP disclosed
EP-2413697-A1 STABILIZATION OF COMPOUNDS COMPRISING IODINE LANXESS Deutschland GmbH (DE) 2012-02-08 EP disclosed
WO-2011000794-A1 POLYMERS CONTAINING HETEROCYCLIC 3-RING COMPOUNDS AND IODINE-CONTAINING COMPOUNDS LANXESS DEUTSCHLAND GMBH (DE) 2011-01-06 WO disclosed
WO-2010142790-A1 INORGANIC CARRIER MATERIALS CONTAINING HETEROCYCLIC 3-RING COMPOUNDS LANXESS DEUTSCHLAND GMBH (DE) 2010-12-16 WO disclosed
WO-2010112387-A1 STABILIZATION OF COMPOUNDS COMPRISING IODINE LANXESS DEUTSCHLAND GMBH (DE) 2010-10-07 WO disclosed
US-20090251643-A1 POLARIZING PLATE, MANUFACTURING METHOD OF POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY APPARATUS KONICA MINOLTA OPTO, INC. (JP) 2009-10-08 US disclosed
EP-1926367-A1 STABILIZATION OF IODINE BIOCIDES Lanxess Deutschland GmbH & Co.KG (DE) 2008-06-04 EP disclosed
WO-2007028527-A1 STABILIZATION OF IODINE BIOCIDES LANXESS DEUTSCHLAND GMBH (DE) 2007-03-15 WO disclosed
EP-1565522-A2 USE OF POLYMER POWDER CONTAINING UV ABSORBER FOR THE STABILISATION OF POLYMERS AGAINST THE EFFECTS OF UV RADIATION BASF AKTIENGESELLSCHAFT (DE) 2005-08-24 EP disclosed
WO-2004046234-A2 USE OF POLYMER POWDER CONTAINING UV ABSORBER FOR THE STABILISATION OF POLYMERS AGAINST THE EFFECTS OF UV RADIATION BASF AKTIENGESELLSCHAFT (DE) 2004-06-03 WO disclosed
WO-2004039877-A2 STABILISING AGENT MIXTURE BASF AKTIENGESELLSCHAFT (DE) 2004-05-13 WO disclosed
US-6353044-B1 PHOTOSTABILITY OF POLYMER WITH BETA-(2,2,6,6-TETRAMETHYL PIPERIDINE-4-AMINO)ETHYL CROTONATE GREAT LAKES CHEMICAL ITALIA S.R.L. (IT) 2002-03-05 US disclosed
EP-0245204-A1 Process for the photochemical stabilization of undyed and dyed fibrous polyamide material and its mixture with other fibres CIBA-GEIGY AG (CH) 1987-11-11 EP disclosed
EP-0114784-A2 Electron-beam curing method for coatings CIBA-GEIGY AG (CH) 1984-08-01 EP disclosed
EP-0002753-A2 Stabilisation of heat-curable metallic enamel paints against the action of light, humidity and oxygen by the addition of polyalkylpiperidine derivatives CIBA-GEIGY AG (CH) 1979-07-11 EP disclosed