Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 8/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | BCR | P11274 | 2/20 | 0.42 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5370431 | 0.99 | CHRNA7 (0.43) | CHRNA7ABCG2ABL1BCRCTSC | |
| SCHEMBL27715058 | 0.92 | CHRNA7 (0.47) | CHRNA7ABL1BCR | |
| Hydrochloric Acid SCHEMBL5364721 | 0.78 | LMNA (0.47) | ABCG2MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL6104626 | 0.78 | ABCG2 (0.57) | ABCG2MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL27695119 | 0.78 | ABCG2 (0.47) | ABCG2BCDIN3D | |
| Hydrochloric Acid SCHEMBL5367305 | 0.77 | CA2 (0.52) | ABCG2ABL1MEN1KMT2APDE4B | |
| Hydrochloric Acid SCHEMBL5360146 | 0.77 | ABCG2 (0.60) | ABCG2MEN1KMT2ATP53LMNA | |
| Hydrochloric Acid SCHEMBL5361695 | 0.77 | ABCG2 (0.56) | ABCG2MEN1KMT2ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL6106002 | 0.77 | ABCG2 (0.46) | ABCG2BCDIN3D | |
| Hydrochloric Acid SCHEMBL5360340 | 0.77 | CHRNA7 (0.48) | CHRNA7ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101107250-A | Novel bicyclic heterocyclic compounds, process for their preparation and compositions containing them | REDDY US THERAPEUTICS INC (US) | 2008-01-16 | — | — | CN | claimed |
| CN-101107250-A | Novel bicyclic heterocyclic compounds, process for their preparation and compositions containing them | REDDY US THERAPEUTICS INC (US) | 2008-01-16 | — | — | CN | disclosed |
| EP-1814885-A2 | NOVEL BICYCLIC HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | Reddy US Therapeutics, Inc. (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006073610-A2 | NOVEL BICYCLIC HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | REDDY US THERAPEUTICS, INC. (US) | 2006-07-13 | — | — | WO | disclosed |
| US-20060128729-A1 | Novel bicyclic heterocyclic compounds, process for their preparation and compositions containing them | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128729-A1 | Novel bicyclic heterocyclic compounds, process for their preparation and compositions containing them | HPSE, ENGASE, UGCG | CHRNA7 4833/4885ABCG2 3081/4885ABL1 4618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.