Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6110055 | 0.80 | KMT2A (0.39) | ALDH1A1IKBKBSMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL3580429 | 0.80 | NOS3 (0.43) | ALDH1A1SMN1; SMN2CYP1A2KDM4EMAPT | |
| SCHEMBL24027298 | 0.78 | SMN1; SMN2 (0.40) | ALDH1A1IKBKBSMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL1858070 | 0.77 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2KDM4EMAPTRAB9A | |
| SCHEMBL20312711 | 0.77 | IKBKB (0.35) | ALDH1A1IKBKBSMN1; SMN2CYP1A2RAB9A | |
| SCHEMBL21599035 | 0.77 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2KDM4EMAPTRAB9A | |
| SCHEMBL1256532 | 0.77 | GRM5 (0.39) | ALDH1A1IKBKBCYP1A2KDM4EP2RX7 | |
| SCHEMBL20209504 | 0.77 | ALDH1A1 (0.38) | ALDH1A1IKBKBSMN1; SMN2MAPTRAB9A | |
| SCHEMBL19857471 | 0.74 | KDM4E (0.48) | ALDH1A1SMN1; SMN2KDM4EMAPTRAB9A | |
| SCHEMBL18013563 | 0.74 | KDM4E (0.49) | ALDH1A1CYP1A2KDM4EMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300901-B2 | Hollow beads of polyethylene | TOTAL PETROCHEMICALS RESEARCH FELUY (BG) | 2007-11-27 | — | — | US | disclosed |
| US-20070054799-A1 | Hollow beads of polyethylene | LAVASTRE OLIVIER | 2007-03-08 | — | — | US | disclosed |