Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 15/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540781 | 0.79 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3HRH1MLNR | |
| SCHEMBL1690392 | 0.77 | CHRM2 (0.37) | CHRM2CHRM1CHRM3 | |
| SCHEMBL15573852 | 0.77 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3HRH1MLNR | |
| SCHEMBL8285438 | 0.76 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3HRH1MLNR | |
| SCHEMBL4596454 | 0.76 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3HRH1MLNR | |
| SCHEMBL4595714 | 0.76 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3HRH1MLNR | |
| SCHEMBL3779945 | 0.76 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3HRH1MLNR | |
| SCHEMBL4595831 | 0.76 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3HRH1MLNR | |
| SCHEMBL1961849 | 0.76 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3HRH1MLNR | |
| SCHEMBL4595727 | 0.76 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3HRH1MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259774-A1 | Enantioselective Phosphoramidite Compounds and Catalysts | YALE UNIVERSITY (US) | 2007-11-08 | — | — | US | disclosed |
| EP-1745056-A4 | ENANTIOSELECTIVE PHOSPHORAMIDITE COMPOUNDS AND CATALYSTS | YALE UNIVERSITY CORP (US) | 2007-10-31 | — | — | EP | disclosed |
| EP-1745056-A2 | ENANTIOSELECTIVE PHOSPHORAMIDITE COMPOUNDS AND CATALYSTS | Yale University Corporation (US) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005111050-A2 | ENANTIOSELECTIVE PHOSPHORAMIDITE COMPOUNDS AND CATALYSTS | YALE UNIVERSITY (US) | 2005-11-24 | — | — | WO | disclosed |
| WO-2004024684-A2 | ENANTIOSELECTIVE AMINATION AND ETHERIFICATION | YALE UNIVERSITY (US) | 2004-03-25 | — | — | WO | disclosed |
| US-4705553-A | Method of reducing plant growth height using phenylalkylmorpholines | BASF AKTIENGESELLSCHAFT (DE) | 1987-11-10 | — | — | US | disclosed |
| US-4434165-A | Fungicidal compositions | HOFFMANN-LA ROCHE INC. (US) | 1984-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259774-A1 | Enantioselective Phosphoramidite Compounds and Catalysts | AKR1C3, PCNA, AKR1C4 | SLC6A2 1539/4885SLC6A4 1416/4885SLC6A3 869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.